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Science
Biology
Immunology
immunity terms
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Terms in this set (31)
antigen
foreign substance, microbes, or component of cell that stimulates immune response
antibody
specific protein produced in humoral response to bind with antigen
autoantibody
Antibodies against self antigen; attacks body's own tissues
thymus
gland in the mediastinum; large in children, decreases in size in adults, site maturation and proliferation of T lymphocytes
lymphatic tissue and organs
Contain many lymphocytes. Filter body fluids, remove foreign matter, immune response
bone marrow
Source of stem cells, leukocytes, and maturation of B lymphocytes
neutrophils
White blood cells for phagocytosis; nonspecific defense; active in inflammatory process
basophils
White blood cells: bind IgE, release histamine in anaphylaxis
Eosinophils
white blood cells; participate in allergic responses and defense against parasites
monocytes
White blood cells: migrate from the blood into tissues to become macrophages
Macrophages
Phagocytosis; process and present antigens to lymphocytes for the immune response
mast cells
Release chemical mediators such as histamine in connective tissue
B lymphocytes
Humoral immunity-activated cell becomes an antibody-producing plasma cell or a B memory cell
plasma cells
Develop from B lymphocytes to produce and secrete specific antibodies
Cytotoxic or killer T cells
Destroy antigens, cancer cells, virus-infected cells
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Verified questions
BIOLOGY
In 1932, H. J. Muller suggested a genetic test to determine whether a particular mutation whose phenotypic effects are recessive to wild type is a null (amorphic) or hypomorphic allele of a gene. Muller’s test was to compare the phenotype of homozygotes for the recessive mutant alleles to the phenotype of a heterozygote in which one chromosome carries the recessive mutation in question and the homologous chromosome carries a deletion for a large region including the gene. In a recent study utilizing Muller’s test, investigators examined two mutant alleles of rugose named $r g^{4 1}$ and $r g^{\gamma{3}}.$ The eye phenotypes displayed by flies of several genotypes is indicated in the following table. Df(1)JC70 is a large deletion that removes rugose and several genes to either side of it. $$ \begin{matrix} \text{Genotype} & \text{Eye surface} & \text{Cone cells per ommatidium}\\ \hline \text{wild type} & \text{smooth} & \text{4}\\ \text{$r g^{4 1} / r g^{41}$} & \text{mildly rough} & \text{$2-3$}\\ \text{$r g^{4 1} / D f(1) J C 70$} & \text{moderately rough} & \text{$1-2$}\\ \text{$r g^{\gamma 3} / r g^{\gamma 3}$} & \text{very rough} & \text{$0-1$}\\ \text{$r g^{\gamma 3} / D f(1) J C 70$} & \text{very rough} & \text{$0-1$}\\ \end{matrix} $$ a. Which allele $(r g^{4 1}$ or $r g^{\gamma{3}})$ is “stronger” (that is, which causes the more severe phenotype)? b. Which allele directs the production of higher levels of functional Rugose protein? c. How would Muller’s test discriminate between a null allele and a hypomorphic allele? Suggest a theoretical explanation for Muller’s test. Based on the results shown in the table, is either of these two mutations likely to be a null allele of rugose? If so, which one?
BIOLOGY
A forest near a city provides drainage for rainfall runoff. A group of citizens is protesting new housing developments in the forest because they believe flooding and property destruction will result. Analyze the value of biodiversity that describes their concern.
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BIOLOGY
Summarize the key concepts that led to the development of the technique for producing chymosin: (a) Concept 1: _____ (b) Concept 2: _____ (c) Concept 3: _____ (d) Concept 4: _____ (e) Concept 5: _____
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