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Respiratory Pharmacology CH. 1-11 Key Terms & Definitions

Terms in this set (139)

Agent that stimulates sympathetic nervous fibers, which allow relaxatio of smooth muscle in the airway; a.k.a. sympathomimetic bronchodilator or beta-2-agonist
adrenergic bronchodilator
Causes vasoconstriction and vasopressor effect; in the upper airway (nasal passages), this can provide decongestion.
alpha-receptor stimulation
Refers to increasing incidence of asthma morbidity, and especially asthma mortality, despite advances in the understanding of asthma and availability of improved drugs to treat asthma.
asthma paradox
Causes increased myocardial conductivity, heart rate, and contractile force.
beta-1-receptor stimulation
Causes relaxation of bronchial smooth muscle, with some inhibition of inflammatory mediator release and stimulation of mucociliary clearance.
beta-2-receptor stimulation
Narrowing of the bronchial airways caused by contraction of smooth muscle.
bronchospasm
group of similar compounds having sympathomimetic action; they mimic the actions of epinephrine.
catecholamines
Nucleotide produced by beta-2-receptor stimulation; it affects may cells, but it causes relaxation of bronchial smooth muscle.
cyclic adenosine 3', 5'-monophosphate (cAMP)
Long-term desensitization of beta receptors to beta-2 agonists caused by a reduction in the number of beta receptors.
downregulation
Producing effects similar to those of the sympathetic nervous system.
sympathomimetic
Agent that blocks parasympathetic nervous fibers, allowing relaxation of smooth muscle in the airway.
anticholinergic bronchodilator
Same as anticholinergic bronchodilator--agent that blocks the effect of acetylcholine (Ach) at the cholinergic site.
antimuscarinic bronchodilator
Agent that produces the effect of Ach.
cholinergic
Same as cholinergic--agent that produces the effect of Ach or an agent that mimics Ach.
muscarinic
Blocking parasympathetic nervous fibers
parasympatholytic
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