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Quiz 5: Liver Function
Terms in this set (21)
Which of the following would be classified as prehepatic jaundice?
b) congestive heart failure
c) rotor syndrome
d)cancer of the bile ducts
Congestive heart failure
The first serological marker of Hepatitis B is:
A breakdown product of bilirubin metabolism that is produced in the colon from the oxidation of urobilinogen by microorganisms is:
Which is a characteristic of unconjugated bilirubin?
a) it is water soluble
b) it reacts faster than conjugated bilirubin
c) it has the same absorbance properties as conjugated bilirubin
d) it a not water-soluble
It a not water-soluble
The cells that make up 70% of the liver's mass are:
a) kupffer cells
c) endothelia cells
d) none of these
In obstructive liver disease, the following test results are found:
Feces: urobilinogen decreased; urine: bilirubin: positive; serum: conjugated bilirubin increased.
In the Jendrassik-Grof bilirubin methodology, what converts purple azobilirubin to blue-green azobilirubin measured at 600 nm?
What breakdown product of bilirubin metabolism is produced in the colon from the oxidation of urobilinogen by microorganisms?
Bilirubin that has been secreted through the bile into the small intestine is reduced by anaerobic microorganisms to urobilinogen. One of the possible fates of urobilinogen is its conversion to urobilin. In the colon, a portion of the urobilinogen is oxidized by the action of microorganisms to urobilin, which is excreted in the feces as an orange-brown pigment.
What is the most common cause of unconjugated hyperbilirubinemia?
a) hemolytic anemia
b) gilberts disease
c) bile duct obstruction
e) neonatal physiologic jaundice
Neonatal physiologic jaundice
Viral hepatitis that results in the largest % of chronic hepatitis is:
a) hep a
b) hep b
c) hep c
d) hep d
If a total bilirubin is 4.0 mg/dl and the conjugated bilirubin is 2.5 mg/dl, the unconjugated bilirubin is?
c.) 1.5 mg/dL
Ligases are a class of enzymes that catalyze:
a) oxidation-reduction reactions
b) the transfer of groups
c) the removal of groups without the addition of water
d) the coupling of two molecules with the use of ATP
The coupling of two molecules with the use of ATP
Enzymes that catalyze the transfer of groups other than hydrogen between compounds are classified as belonging to which enzyme class?
Many enzymes in the blood plasma show maximum activity in which of the following pH ranges?
a) 4 to 5
b) 6 to 7
c) 7 to 8
d) 8 to 9
7 to 8
Aspartate aminotransferase is elevated in diseases involving the:
a) renal cortex
b) heart muscle
c) intestinal epithelium
d)acing cells of the pancreas
The highest levels of alkaline phosphatase are seen in:
a) instructive liver disease
c) renal failure
d) myocardial infarction
Obstructive liver disease
A model for end-stage liver disease staging system to predict prognosis in cirrhosis uses the following laboratory determinations EXCEPT:
d) Aspartate transaminase
Serum lipase catalyzes:
a) hydrolysis of triglyceride to fatty acids and glycerol
b) hydrolysis of triglyceride to fatty acids and water
c) synthesis of triglyceride from fatty acids and water
d) synthesis of triglyceride from fatty acids and glycerol
hydrolysis of triglyceride to fatty acids and glycerol
In competitive inhibition of an enzyme reaction:
a) the inhibitor binds to the enzyme at the same site as does the substrate
b) the inhibitor often has a chemical structure different than the substrate
c) activity of the reaction can be decreased by decreased by increasing the concentration of the substrate
d) activity of the reaction can be increased by decreasing the temperature
the inhibitor binds to the enzyme at the same site as does the substrate
Which of the following would NOT show an increase in alkaline phosphatase?
a) obstructive liver disease (hepatobiliary) rickets
the protein part of the enzyme molecules WITH the cofactor is called an
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