Obesity: The best way to save food and survive the next famine in our EEA is to eat it all. Food expires, but fat stays. Therefore, we should eat as much as we can. However, because of easy access to food, this leads to obesity. As such, our tendency to eat as much food as possible is a maladaptive behavior and demonstrates conflict between our genes and our alien world.
Altruism to strangers: In our EEA, we should look for every opportunity to improve our relationships within our groups. Since we lived in relatively small groups, word about reputation spreads quickly. However, nowadays, we see thousands of different people a day and will most likely never meet them again. Being altruistic comes at a cost to us which may never be paid back because we lack multiple interactions. However, we still do it expecting compensation because of our EEA.
Drugs: Our endocrine system works around the interaction between neurotransmitters and receptors. However, our receptors activate whenever a molecule that resembles the target NT is able to fit in the "key"; it never knows if it is the actual NT or not. Drugs are made to take advantage of this recognition issue. They may resemble our NT but act differently at the synapse. Therefore, it has become maladaptive because drugs, which weren't in our EEA, can hijack our endocrine system due to this flaw.