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Allergy and Hypersensitivity

Terms in this set (16)

I
IgE antibodies are responsible for Type ______ hypersensitivity.
- Histamine
- Heparin
- Proteases
- Prostaglandins
- Chemokine
- Leukotrienes
What molecules are released during degranulation?
parasitic
Healthy people only make IgE in response to what type of infection?
atopic
Individuals who produce IgE against common environmental antigens are referred to as ______________.
H1
Which receptor does an antihistamine target (to block and bind)?
1st
Benadryl is a _________ generation antihistamine.
Upon contact through the skin at an early age; proved by filaggrin deficiency
How do food allergies develop?
C) FcεRI
Which of the following cell-surface receptors is MOST closely linked to activating type
I hypersensitivity reactions?
A) FcεRII
B) FcγRIIB
C) FcεRI
D) LFA-1
E) None of the answers are correct.
FcεRI
_________________ is a high-affinity IgE receptor and is responsible for most allergy symptoms.
FcεRII
_____________ is a low- affinity IgE receptor and regulates the production of IgE by B cells.
true
T/F: Hay fever is a localized hypersensitivity reaction.
E) All of the answers are correct.
Which of the following cell types are targets of the products of mast-cell degranulation,
as well as the mediators produced by mast cells following degranulation?
A) Smooth muscle
B) Nervous tissue
C) Hematopoietic cells
D) Epithelial cells
E) All of the answers are correct.
B) Suppression of mast-cell degranulation
Which of the following effects is NOT a result of histamine binding to histamine
receptor H1?
A) Intestinal smooth muscle contraction
B) Suppression of mast-cell degranulation
C) Increased vascular permeability
D) Increased mucous secretion
E) All of the answers result from histamine binding H1.
D) TGF-β
Which of the following cytokines is NOT generally associated with allergic reactions?
A) TNF-α
B) GM-CSF
C) IL-4
D) TGF-β
E) All of the answers are associated with allergic reactions
C) bee sting
The immune response to a peanut allergy is MOST similar to a
A) poison ivy rash.
B) positive PPD test.
C) bee sting.
D) transfusion reaction.
E) None of the answers are similar.
E) All of the answers are correct.
Which of the following is a potential cause of chronic inflammation?
A) Obesity
B) Infectious agents
C) Tissue damage
D) Intestinal commensal microbiota components
E) All of the answers are correct.
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