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Science
Medicine
Drugs used in Erectile Dysfunction and Androgens Replacement Therapy
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Terms in this set (32)
what group of drugs Nandrolone is ? And what is the Clinical indication?
Androgens, for females with wasting condition
what group of drugs Testesterone is ? What is the Route of Administration?
Androgens , subcutaneous implantation or transdermal patches.
What group of drugs Methyltestosterone ? What is the Route of Administration?
Androgens , orally
Clinical indications of androgens
Loss of libido , hypogonadism in males (delayed puberty) ,athletes
Side effect of androgens
1. infertility ( Decrease of gonadotrophin release)
2. Edema
3.Adenocarcinoma of the liver.
4.Impair growth in children
5. Acne , girls masculinisation
What is the group of drugs Flutamide, what is the clinical indication
Anti-androgens , prostatic carcinoma.
What is the group of drugs Cyproterone acetate, what is the clinical indication
Anti-androgens , men : excessive sexual females: hirsutism
What is the group of drugs Finastride, what is the clinical indication
Anti-androgens, benign prostatic hyperplasia
What drug causes irreversible erectile dysfunction?
Finastride
What is tumescence?
Penile erection caused by fullness of blood in Corpora cavernosa in penis
What is impotence?
erectile dysfunction
What is priapism?
prolonged erection
What is the effect of Tricyclic Antidepressants in reproductive system ?
erectile dysfunction
What is phenytoin used for? And what is the side effect ?
Anti-epileptics , erectile dysfunction ( because the drug is centrally acting it will cause decrees libido and)
What is calcium channel blockers used for and what is the side effect ?
Anti-hypertensive Drugs , erectile dysfunction
What are these drugs used for ( B2 blockers, α-agonists,) and what is the side effect ?
Anti-hypertensive Drugs , erectile dysfunction
What are these drugs used for , and what is the side effect (as methyl dopa, reserpine & clonidine)
Centrally acting anti-hypertensives , vasoconstriction
peripherally which leads to erectile dysfunction
What is the side effect of cimetidine?
hyper-prolactinemia or gynecomastia and erectile dysfunction
What is the side effect of ketoconazole?
hyper-prolactinemia or gynecomastia and erectile dysfunction
What is the side effect of spironolactone?
hyper-prolactinemia or gynecomastia and erectile dysfunction
What is the side effect of Estrogen-containing medications?
hyper-prolactinemia or gynecomastia and erectile dysfunction
What is phentolamine used for ? And what the mechanism of drug ?
treating erectile dysfunction, Alpha 1 adrenoceptor blocker
What is the first line of treatment of erectile dysfunction Peripherally?
sildenafil and vardenafil
What is the mechanism of action of sildenafil and vardenafil ?
Phosphodiesterase 5 (PDE5) Inhibitors
Mechanism of action of alprostadil?and what is the clinical indication ?
Prostaglandin E1 (PGE1) analogues, erectile dysfunction
What is the drug that inhibit PDE2,3,4?
papaverine
What is minoxidil used for? Other than hypertension
erectile dysfunction
Nitrates (nitroglycerin) is contraindicated for ?
patient with chest pain who has taken Viagra recently (in the last 24 hours).
( Penile pain, Urethral bleeding or infection,Hypotension, Priapism) are side effect of ?
alprostadil ( Prostaglandin Analogue)
What are the drugs that are given topically to treat erectile dysfunction?
Minoxidil, papaverine
What are the drugs that are given by intra-cavernosal injection to treat erectile dysfunction?
phentolamine, papaverine
phenylephrine is used for ?
Priapism
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