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Introduction to the clinical laboratory/principles of analysis Ch: 10 Clinical Chemistry
Terms in this set (70)
Creatinine concentration in the blood has a direct relationship to?
-dietary protein intake
-age and gender
Creatinine clearance is used to assess the?
Glomerular filtration capabilities of the kidneys
Expected creatinine clearance for a patient with chronic renal disease would be?
very low; renal glomerular filtration is not functioning normally
Testing blood from a patient with acute glomerulonephritis would most likely result in which of the following laboratory findings?
Which of the following lipid results would be expected to be falsely elevated in a blood specimen drawn from a non-fasting patient?
What is a hyperlipidemic condition exists for a sufficient time, it may be associated with the development of which of the following conditions?
In what major organ of the body is the majority of the body's cholesterol synthesized?
Which cardiac marker persists at the highest concentration for the longest length of time?
Tumor markers include?
-Carcinoembryonic antigen (CEA)
-Beta subunit of human chorionic gonadotropin
Highest volume testing department in the lab is?
Major revenue generator for the lab?
Lab testing associated with atherosclerosis?
Lab testing associated with diabetes mellitus?
-glucose tolerance testing
Lab testing associated with renal failure?
-glomerular filtration rate
Lab testing associated with myocardial infarction?
Lab testing associated with congestive heart failure?
B-type Natriuretic Peptide
Lab testing associated with sepsis?
Lab testing associated with hepatitis( acute/chronic)?
-AST< ALT< A1K, Phos, ammonia
Lab testing associated with cirrhosis?
Lab testing associated with pancreatitis?
-amylase, lipase, IRT
Lab testing associate thyroid disease?
-thyroxine, TT4, T3, Tuptake
Lab testing associated with reproductive diseases?
FSH, LH, Estradiol, Testosterone
Lab testing associated with adrenal diseases?
Lab testing associated with tumor markers?
-Carcinoembryonic antigen (CEA)
-Prostate-specific antigen (PSA)
Lab testing involved in peak and trough levels of therapeutic drug monitoring?
Lab testing involved with therapeutic levels of therapeutic drug monitoring?
Lab testing involved in toxicology poisoning?
-drugs of abuse
Lab test involved in cardiac inflammation?
Lab testing involved in metabolic acidosis, metabolic alkalosis, respiratory acidosis and respiratory alkalosis?
-blood gas (pH, pO2, pCO2)
Lab testing involved with dehydration?
-lytes (Na, K, Cl, CO2)
Lab testing involved with vomiting (excessive)?
Lab testing involved with diarrhea (excessive)?
Arthrosclerosis is a disease of?
Diabetes mellitus is a disease of?
What are the 2 main purposes of CA15-3/CA27.29 assay are?
1: to monitor disease progression and/or response to therapy in patients with metastatic breast cancer
2: to detect cancer recurrence in patients treated previously for stages II or III breast cancer who are clinically free of the disease
What is CA15-3/CA27.29 is not recommended as an assay for?
breast cancer screening
Its main use is as a marker for colorectal and pancreatic carcinoma?
Levels of CA 19-9 are elevated in patients with?
pancreatic, hepatobiliary, colorectal, gastric, hepatocellular, pancreatic and breast cancers.
The CA 125 marker is elevated in?
carcinomas and benign disease of various organs including pelvic inflammatory disease and endometriosis
The CA 125 marker is most useful in?
ovarian and endometrial carcinomas
Carcinoembryonic antigen (CEA) plasma levels greater than 12ng/mL are strongly correlated with?
20% of smokers and 7% of former smokers have?
elevated Carcinoembryonic antigen levels
Carcinoembryonic antigen (CEA) is used clinically to?
monitor tumor progress in patients with who have diagnosed cancer with a high blood CEA level.
If treatment leads to a decline in normal CEA levels, then an increase in CEA levels may indicate?
A persistent high level of CEA is indicative of what?
residual disease or poor theraputic response
prostate-specific antigen (PSA)
blood test used to screen for prostate cancer
PSA screening may reduce prostate cancer mortality risk but is associated with?
false-positive results, biopsy complications, and over diagnosis
Blood levels of PSA are increased when normal glandular structure is disrupted by?
benign or malignant tumor inflammation
glucose tolerance test
A test of the body's ability to metabolize glucose.
A test that measures the level of hemoglobin A1c in the blood as a means of determining the average blood sugar concentrations for the preceding two to three months.
Electrolytes (Na, K, CL, CO2 are the major four)
Difference between the concentrations of serum cations and anions: determined by measuring the concentrations of sodium cations and chloride and bicarbonate anions.
anion gap test is associated with?
A person with excessive diarrhea will be tested for?
calcium and magnesium
Test associated with metabolic acidosis, metabolic alkalosis, respiratory acidosis and respiratory alkalosis?
test that measures the level of creatinine in blood to estimate how well the kidneys are filtering
BUN test associated with renal failure?
blood urea nitrogen test
Glomerular filtration rate associated test with renal failure?
amount of filtrate formed in all the renal corpuscles of both kidneys each minute
blood test that measures the levels of triglycerides in the blood
determine whether your cholesterol is high and estimate your risk of developing heart attacks and other forms of heart disease and diseases of the blood vessels
concentration of low-density lipoproteins in the blood
concentration of high-level lipoproteins in the blood
troponin 1 test
measures the levels of troponin I proteins in the blood.
troponin T test
measures levels of troponin T levels in the blood
B-type natriuretic peptide (BNP)
It measures the level of B-type natriuretic peptide in your blood
C-reative protein (CRP)
blood test that is elevated as a non-specific marker of inflammation
lab for bacteremia and septicemia
AST,ALT Alk, phos, ammonia are associated tests for?
Chemistry test to assess liver function
Amylase, lipase, IRT
tests for pancreatitis
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