Upgrade to remove ads
10. Bronchial asthma
Terms in this set (30)
What is asthma?
-chronic inflammatory disorder of the airways
asthma is a _______ inflammatory disorder of the ________
chronic and airways
What is asthma characterized by?
-reversible airflow obstruction
-manifests as reversible cough, wheezing and dyspnea
Asthma is characterised by bronchial _____-______________, asthma _______ and reversible airflow ___________
Allergic asthma (extrinsic) is what?
Usually develops in childhood and is triggered by allergens (pollen, certain food, dust). this asthma is associated with atopy
Which type of asthma is associated with atopy?
Allergic asthma (extrinsic)
non-allergic asthma (intrinsic) is what?
usually develops in patients over 40 and has various triggers such as cold air, medications, viral infections, exercise . this type of asthma is not related to atopy
allergic asthma (extrinsic) usually develops in _________ and is triggered by _________ (pollen, certain food, dust). this asthma is associated with _____
which type of asthma is not associated with atopy?
non-allergic asthma (intrinsic)
What are the risk factors associated with asthma?
asthma is an inflammatory disease driven by _-______ 2 cells
Causes of asthma include:
-gastro oesophageal reflux
mediators such as histamine, prostaglandins and leukotrienes ________ airway smooth muscle, increase microvascular _______, increase mucus _________
Asthma is an inflammatory disease driven by which type of cell?
T-helper 2 cells
Allergic asthma is ___ mediated type 1 hypersensitivity to a specific ________. This is characterised by ____ cell degranulation and release of __________ after a phase of _____________
non-allergic asthma is when an ________ enter the lungs---> release of ___________--->submucosal ______---> airway ___________
Bronchial inflammation is allergic asthma is caused by inflammation of the terminal ___________ because of:
over expression of _-_______ cells--->_________ production (IL-2, IL-4, IL-5, IL-13)---> activation of ____________ and ___-cell IgE production---> bronchial submucosal ______ and smooth muscle ___________--->bronchiole collapse
Aspirin induced asthma is a non-allergic type of asthma. the process includes:
__________ of cox-1---> decreases in _______________---> increased leukotrienes and ____________--->submucosal ______--->airway ___________
Patient anamnesis includes:
-coughing (dry cough which worsens at night)
-end expiratory wheezing
-increased ventilation and use of accessory muscles
on inspection of an asthmatic patient they will show>
-accessory muscle use
-in children (supraclavicular and intercostal retractions and nasal flaring and abdominal breathing)
-may not be able to speak fluently
-enlarged jugular veins
on palpation they patient presents:
-weak vocal fremitus
percussion shows a _____________ sound and wide _______ spaces
Auscultation shows weak _________ breathing and prolonged __________. wheezing and tachycardia may also be present
What investigation/lab tests can be done for asthma?
-Haematology (eosinophils, IgE)
-Sputum (Eosniophilia, charcot crystals and curschmann spirales)
-Lung function tests (reduced FEV1, FEV1/FVC ration and PEF)
Lung function tests of an asthmatic patient shows _________ FEV1, _________ FEV1:FVC ratio and peak expiratory flow rate
What lung function tests are decreases in asthmatic patients?
Peak expiratory flow rate
Sputum analysis of an asthmatic patient will show
sputum analysis of an asthmatic patient will show __________ spirals, _______ crystals and ______ bodies
what complications are associated with asthma?
-flare ups lasting hours
-arterial pulmonary hypertension
-chronic cor pulmonale
medication that can be used for asthma include
-beclomethasone (inhaled corticosteroid)
THIS SET IS OFTEN IN FOLDERS WITH...
6. Auscultation of lungs - normal sounds. 7. Added…
9. Acute and chronic bronchitis
39. Myocardial infarction
OTHER SETS BY THIS CREATOR
27. Blunt thoracic and abdominal injuries
33. Principles of wound's treatment
45. Inflammation. Morphological changes. Pathophys…
54. Tuberculosis. Types of surgical tuberculosis.…
OTHER QUIZLET SETS
BIO 1008 - Ch. 47
Module 5 Gastrointestinal Exam
Matter and Energy Review
Final exam animal behavior part 4