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Drugs for Nurs 3110 Final

Terms in this set (20)

Albuterol (Proventil, Ventolin, Proair)
Drug class: inhaled beta 2 agonist

MOA: works to relax the bronchial smooth muscle/ inhibits the release of immediate hypersensitivity mediators from cells

indications: treatment/prevention of bronchospasm (acute or severe) in patients with reversible obstructive airway disease, including exercise-induced bronchospasm.
Prednisone
drug class: corticosteroid

MOA: decreased vasodilation and permeability of capillaries, as well as decreased leukocyte migration to sites of inflammation

indications: to treat the symptoms of low corticosteroid levels
Diphenhydramine (Benadryl)
drug class: antihistamine

MOA: inverse agonist at the H1 receptor, thereby reversing effects of histamine on capillaries, reducing allergic reaction symptoms.

indications: used to relieve symptoms of allergy, hay fever, and the common cold.
Ondansetron (Zofran)
drug class: antiemetic

MOA: Ondansetron is a selective 5-HT3-receptor antagonist which blocks serotonin, a natural substance that may cause nausea and vomiting.

indications: Cancer chemotherapy-induced nausea and vomiting
Docusate sodium (Colace)
drug class: laxative/stool softener

MOA: It works by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass.

uses: constipation
Omeprazole (Prilosec)
drug class: proton pump inhibitor

MOA: It inhibits the parietal cell H+ / K+ ATP pump, the final step of acid production.

Uses: is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers).
Levothyroxine (Synthroid)
drug class: thyroid hormone

MOA: It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland.

Uses: hypothyroidism/Pituitary thyrotropin-stimulating hormone suppression
Metformin (Glucophage)
drug class: Antidiabetic Agent, Biguanide

MOA: decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Uses: Diabetes mellitus, type 2 (hyperglycemia cannot be managed with diet and exercise)
Insulin aspart (Novolog)
Drug class: fast acting insulin

MOA: bind to the insulin receptors on muscle and fat cells and lower blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the liver.

Uses: improve glycemic control of Diabetes mellitus, types 1 and 2
Insulin detemir (Levemir)
Drug class: insulin, long acting

MOA: exert their specific action through binding to insulin receptors. Receptor-bound insulin lowers blood glucose by facilitating cellular uptake of glucose into skeletal muscle and fat and by inhibiting the output of glucose from the liver.

uses: improve glycemic control of Diabetes mellitus, types 1 and 2
Glimepiride (Amaryl)
Drug class: sulfonylureas

MOA: lowers blood sugar by causing the release of your body's natural insulin via the pancreas

uses: Diabetes mellitus, type 2, adjunct to diet & exercise
Ethinyl estradiol/norgestimate (Ortho Tri-Cyclen)
Drug class: Estrogen and Progestin Combination Contraceptive

MOA: inhibit ovulation via a negative feedback mechanism on the hypothalamus, prevents egg from fully developing

Uses: acne and birth control
Medroxyprogesterone acetate (Depo-Provera)
drug class: Progestin Contraceptive

MOA: transforms a proliferative endometrium into a secretory endometrium; inhibits secretion of pituitary gonadotropins, which prevents follicular maturation and ovulation and causes endometrial thinning

Uses: contraception, endometriosis pain
Conjugated estrogens/medroxyprogesterone acetate (Prempro)
Drug class: Estrogen and Progestin Combination

MOA: Conjugated estrogen: development and maintenance of the female reproductive system and secondary sexual characteristics
Postmenopausal → modulate the pituitary secretion of gonadotropins, LH, and FSH through a negative feedback system; estrogen replacement reduces elevated levels of these hormones in postmenopausal women.
Progestrin (medroxyprogesterone) → transforms a proliferative endometrium into a secretory endometrium

uses: Prevention of postmenopausal osteoporosis; Vulvar and vaginal atrophy & vasomotor symptoms associated with menopause (low estrogen)
Testosterone transdermal (AndroGel)
drug class: androgens

MOA: a gel that uses testosterone is absorbed via the skin to help low testosterone levels

uses: Hypogonadotropic Hypogonadism (HH; congenital or acquired); primary hypogonadism
Tamsulosin (Flomax)
drug class: alpha 1 blocker

MOA: antagonist of alpha1A-adrenoreceptors in the prostate; blocking them leads to relaxation of smooth muscle in the bladder neck and prostate causing an improvement of urine flow and decreased symptoms of BPH.

uses: BPH
Alendronate (Fosamax)
drug class: Bisphosphonate

MOA: :inhibits bone resorption via actions on osteoclasts or on osteoclast precursors → indirect increase of bone density

uses: paget disease, osteoporosis
Ibuprofen (Advil/Motrin)
Drug class: NSAIDS

MOA: Reversibly inhibits COX-1 and 2 enzymes

uses: Inflammatory diseases and rheumatoid disorders, mild to moderate pain, fever, dysmenorrhea, osteoarthritis
Calcium carbonate (TUMS)
Drug class: Antacid

MOA: neutralize gastric acidity

uses: relief of acid indigestion, heartburn, sour stomach, and GI upset associated with these symptoms; calcium supplement
Acetaminophen (Tylenol)
Drug class: Nonopioid Analgesics

MOA: activation of descending serotonergic inhibitory pathways in the CNS

uses: pain and fever
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