Upgrade to remove ads
Only $35.99/year

antineoplastic drugs

Terms in this set (21)

antimetabolite
Methotrexate
methotrexate (antimetabolite) indications
RA, psoriatic arthritis, psoriasis, leukemia
bleomycin, doxorubicin (antibiotics) indication
Lymphoma, testicular, squamous cell
alkylating agent
cyclophosphamide, cisplatin
Cyclophosphamide, cisplatin (alkylating agent) indication
Testicular, ovarian, and bladder
mitotic inhibitor
vincristine
Vincristine (Mitotic Inhibitors) indications
Leukemia, lymphoma
hormone manipulator
tamoxifen
tamoxifen indications
breast cancer
Methotrexate adverse effects
Hepatotoxic
Bone marrow suppression
bleomycin, doxorubicin adverse effects
GI toxicity, skin reactions
Cardiac toxicity, alopecia, red urine, bone marrow suppression
cyclophosphamide adverse effects
hemorrhagic cystitis
cisplatin adverse effects
neuro and nephrotoxic
vincristine adverse effects
CNS effects, GI toxicity, alopecia,inappropriate secretion of ADH (monitor urine output)
tamoxifen adverse effects
Menopause sx, bone marrow depression, CNS depression, GI toxic, visual changes
drugs that can prevent/ treat nausea and vomiting when taking antineoplastic drugs
dronabinol, ondansetron (antiemetics)

alprazolam, lorazepam (benzos)

corticosteroids (dexamethasone)

metoclopramide (gi stimulant)
how to manage bone marrow suppression when on antineoplastics
decreased wbc - filgrastim (neupogen)

decreased rbc - epoetin alfa (epogen, procrit)

**BMS is the major reason for changes in schedules and doses of antineoplastics
how to manage alopecia
Cover head with wig, hat, or scarf in extreme temperatures
how to manage fatigue
•Plan rest periods •Safety measures
how to manage nutrition
•Small frequent meals
•Hydration
•Mouth care
Safe administration
•Wear Gloves, gown, mask
•Receive Specific training
•Avoid skin, eye contact with the medications
•2 certified nurses check the orders and check medication prior to administration

•Extravasation
•Best treatment is prevention
•Treatment
-Specific antidote for each drug•\
Sets found in the same folder