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MB521 Enteric Gram Negative Rods (E. Coli)
Terms in this set (12)
Name three body systems which can be affected by E. coli infections.
CNS, Lower respiratory tract, Bloodstream, GI tract, Urinary tract
In addition to the general virulence factors possessed by all members of the family Enterobacteriaceae, Escherichia strains have specialized virulence factors. Name the two general categories of these factors:
Name the five strains of E. coli which cause gastroenteritis:
Enterotoxigenic, Enteropathogenic, Enteroaggregative, Enterohemorrhagic, Enteroinvasive
What toxins are produced by ETEC?
Heat labile, and heat stable
What other bacteria produces a toxin which is structurally and functionally similar to the E.coli LT1 toxin?
Vibrio cholera, cholera toxin
How does the ETEC toxin cause diarrhea (hint - it is the same as cholera toxin)?
Increase cAMP levels, enhancing chloride secretion and decreasing sodium absorption, causing diarrhea
Where are the genes coding for the attachment factors for the EPEC bacterium?
On a pathogenicity island (called "locus of enterocyte effacement) on a plasmid
Which of the E.coli strains cause what is called considered "traveler's diarrhea"?
Which E. Coli strain agglutinized into a "stacked brick" arrangement?
What disease can be caused by EHEC?
Hemorrhagic colitis with bloody diarrhea, vomiting, abdominal pain.
Which E. coli strain is associated with acute renal failure?
What are some other, extraintestinal diseases are caused by E. coli strains?
UTI, neonatal meningitis, septicemia.
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