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EN13 - Bacterial and Parasitic Sexually Transmitted Diseases

Terms in this set (17)

BACTERIAL VAGINOSIS
Decrease in numbers of Lactobacillus = causes a decrease in what ? _ KNOW THIS
normal vaginal pH is < what ?
what two bacteria will increase?
what azole can we use to treat ? and what else can we do to treat - kinda weird ?
Decrease in numbers of Lactobacillus, decrease in acidity
normal vaginal pH is <4.5

Increase in Gardnerella vaginalis and Peptostreptococcus

Metronidazole - transfer donation of micriobiota into another vaginia
Gonorrhea
gram pos or neg? cocci or rod?
what is the name of the bacteria?
Men: painful what?
Women - mild symptoms so they usually do what?
•Uses what to attach to non-ciliated epithelium? - every bacteria uses this for attachment?

•Evades immune system by phase variation of what?, what covering? and makes an what immunoglobulin protease?
•Caused by Neisseria gonorrhoeae
, gram- cocci (Gonococcus)

Men: painful urination
•Women: milder burning, often overlooked
•Uses pili to attach to non-ciliated epithelium

•Evades immune system by phase variation of pili, capsule-like covering and makes an IgA protease
Effects of Gonorrhea
Men: where does it occur?, can lead to what of the and urinary tract infections?
scar tissue can lead to what in men?

Women - cause PID which is what?
scar tissue can lead to what in fallopian tubes women?
what percent are asymptomatic in women?
if escaped the tubes it causes Fitz-Hugh-Curtis syndrome- found where in the body?
Men: in urethra, can lead to scarring and urinary tract infections
scar tissue can lead to sterility

Women - pelvic inflammatory disease (PID)
- scar tissue in fallopian tubes can obstruct passage of eggs and lead to sterility, or cause ectopic pregnancy

•Approximately 50% asymptomatic

Fitz-Hugh-Curtis syndrome- in liver
Effects of Gonorrhea in Infants: passage through birth canal can lead to what infections? what neonatorum?
Infection is apparent within how many days?
what percent silver nitrate? or what percent erythromycin?
can lead to eye infection and blindness, Ophthalmia neonatorum
Infection is apparent within 5 days
Today, 1% silver nitrate or 0.5% erythromycin
Gonorrhea: Due to growing drug resistance recommended treatment is - what two drugs? A. C

Adult Gonococcal what junctiviits?
Ceftriaxone (cephalosporin) + azithromycin

Adult Gonococcal
keratoconjunctivitis
Chlamydia trachomatis
obligate intracellular or extracellular bacteria?
lacks what in its cell wall?
•Use host cell ATP: "energy parasites"

KNOW TWO FORMS - Which is the replicating form?
elementary body (EB) - what form? infectious or non?
reticulate body (RB) - what form? infectious or non?
obligate intracellular bacteria
lacks peptidoglycan layer

elementary body (EB) - infectious

reticulate body (RB) - larger and noninfectious - replicating
Chlamydia as an STD
is this the most freq reported infectious disease?
•Asymptomatic in what percent of women and what percent of men?
•40% of untreated women develop what that occurs also in Gonorrhea?
•Treatment:
A. D
•Most frequently reported infectious disease in U.S.
•Asymptomatic in 75% of women and 50% of men
•40% of untreated women develop PID

•Treatment:
azithromycin or doxycycline
Chlamydia as an STD
Men: infect where similar to ghon? and can spread to what?, can it cause sterility?
Women: can spread to what 3 places in women similar to ghon? can it cause sterility?

Many people fail to develop long or short-term immunity? -KNOW THIS IN RED
Men: infect urethra and can
spread to epididymis, sterility

Women: infect vaginal canal and can
spread to cervix, uterus and fallopian tubes, causing PID and sterility, ectopic pregnancy

FUC

Many people fail to develop
long-term immunity
Chlamydia Trachoma
•Chronic keratoconjunctivitis - which leads to what?
transmitted what to what?
what type of flies?

Adult Inclusion Conjunctivitis - what is growing in adults?

Neonatal Inclusion Conjunctivitis -develop when? what type of cough is developed?
•Leading cause of preventable blindness
•Transmitted: eye-to-eye
-Eye-seeking flies

Adult Inclusion Conjunctivitis - chlamydia, corneal scaring

Neonatal Inclusion Conjunctivitis- •Acquired during birth
-Distinctive staccato cough
LGV: Lymphogranuloma Venerum
it is the uncommon form of
•Painless what appears?
•During second stage:
-Inflammation of draining what?
-Nodes do what and may rupture?
•Treat with doxycycline for for how many days?
•Uncommon form of Chlamydia. trachomatis infection

•Painless papule or ulcer appears

•During second stage:
-Inflammation of draining lymph nodes
-Nodes enlarge and may rupture

•Treat with doxycycline for 21 days
Syphilis
whats the bacteria name?
what shape - Rod, cocci, spiral? gram pos or neg?
•Infectious dose, is how much?
-bacteria lack what cycle ?
•Transmission is most likely during primary or secondary syphilis?
Treponema pallidum
spirochete
gram-negative
•Infectious dose, 100
-bacteria lack TCA cycle

•Transmission is most likely during primary syphilis
Tuskegee Syphilis Study - they monitored untreated what individuals?
Tuskegee Syphilis Study - monitored untreated African Americans from 1932-1972
Progression of Syphilis
primary syphilis- is this the most infectious?
what is made that we learned in another lecture?

secondary syphilis - known as what?
what is made on mucus membrane? what's the color? is this found in the oral cavity?
what rash develops?
is this infectious?

tertiary syphilis
is this a hypersensitivity reactions?
can lead to what 3 things in this?
is this infectious
what can you develop?
primary syphilis - hard chancre (painless),
most infectious

•of secondary syphilis
- known as "the great imitator"
whitish patches on mucus membranes, including in oral cavity
Maculopapular Rash
highly infectious

tertiary syphilis
due to hypersensitivity reactions
- blindness
- stroke (nervous system)
- mental illness, general paresis: "neurosyphilis
can make GUMMAS
NO not infectious
Treat with what antibiotics: for syphilis? - KNOW THIS IN RED
Latent syphilis - can it last for years or decades?

Tertiary syphilis -
•destruction of what tissues?
can it develop on any organ?
is it infectious?
Treat with antibiotics: penicillin
YES IT CAN

Tertiary syphilis -
•destruction of organs/tissues
May involve any organ
•Not infectious
Congenital syphilis
causes on what on the teeth?
molars what's it called and incisors what's it called?
what of the maxilla and what of the mandible?
High or low palatal arch?
is this contagious? _ KNOW THIS
•Treat mother with antibiotics prior to what of pregnancy?
Hutchinson Teeth
Mulberry Molar
-short maxilla, protruding mandible
-High palatal arch
-Not contagious
•Treat mother with antibiotics
prior to month 4 of pregnancy
Chancroid
whats the bacteria name ?
gram pos or neg? shape
chatericagrized by what that is found in primary syphilis but its soft?
•progresses to very painful genital what?
•Haemophilus ducreyi (gram-negative rod)
soft chancre
•progresses to very painful genital ulcerations
Trichomoniasis
name?
is it a bacteria? _ KNOW THIS, is it pro or eukaryotic?
has what for movement?
is it usually asymptomatic in males and females?
•Trichomonas vaginalis
•Eukaryotic STI - NOT Bacterial

•Flagellate
•Usually asymptomatic in males, some females
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