Robbins Study Guide Chapter 13 White Cells, Lymph Nodes, Spleen, and Thymus

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what are the 2 essential properties that are required for the maintenance of hematopoiesis
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Terms in this set (37)
what are the 5 subtypes of hodgkin lymphomanodular sclerosis mixed cellularity lymphocyte predominance lymphocyte depletion lymphocyte richthe most common type of hodgkin lymphoma isnodular sclerosiswhat are the 3 categories of myeloid neoplasiaacute myelocytic leukemia myelodysplastic syndromes myeloproliferative disorderswhich myeloid neoplasia is characterized by accumulation of immature myeloid cells in the bone marrowacute myelocytic leukemiawhich myeloid neoplasia is associated with ineffective hematopoiesis and associated with cytopeniasmyelodysplastic syndromeswhat are the 3 major symptoms related to depression of marrow function in ALLanemia neutropenia thrombocytopeniaall forms of burkitt lymphoma are associated with translocations of the __________C-Myc gene on chromosome 8what is the most common cancer of childrenacute lymphoblastic leukemiawhat is the most common form of leukemia in adults in the western worldchronic lymphocytic leukemia____________ is a group of clonal stem cell disorders characterized by maturation defects resulting in ineffective hematopoiesis and an increased risk of transformation to AMLmyelodysplastic syndromethe most common cytogenetic finding associated with CML isthe philadelphia chromosome (9;22) (q34;q11)the most common gross finding in the spleen in patients with hodgkin disease issplenomegalywhat are the 5 types of plasma cell dyscrasias (monoclonal gammopathies)multiple myeloma waldenstrom macroglobulinemiathe light chain proteins found in patients with plasma cell dyscrasias are known as ___________bence jones proteinsmultiple myeloma most frequently involved which organ systemskeletal systemradiographically, the lesions seen in multiple myeloma are1-4cm punched out defectslangerhans cells are varibly admixed with eosinophils, lymphocytes, plasma cells and neutrophils, eosinophils are usually a prominent component of the infiltrate. this is the histologic components of _________eosinophilic granulomawhat are the 3 components of hand schuller christian triadcalvarial defects diabetes insipidus exophthalmosthe ___________ of the spleen consists of an artery with an eccentric collar of lymphocytes, the so called periarteriolar lymphatic sheath that expands to form lymphoid noudles composed of B lymphocytes which are capable of developing into germinal centerswhite pulpwhat are the 4 major functions of the spleen that impact disease statesphagocytosis antibody production hematopoiesis sequestration of form blood elementsaccessory spleens or ________ are common autopsy findingsspleniculithe most common cause of massive congestive splenomegaly is ____________cirrhosis of the liverdescribe the gross appearance of splenic infarctspale, wedge shaped, and subcapsular in location and the overlying capsule is covered with fibrinwhat are the 2 most common neoplasms of the spleenlymphangioma and hemangiomawhat are the 2 types of cancer in which there is splenic involvementmyeloid and lymphoid tumorsat what age does thymic involution beginpuberty_____________ are the whorls of keratinized cores of epithelial cells in the thymus medulla that are densely packed, often spindle shaped and ahve scant cytoplasm devoid of interconnecting the processes.hassall corpsucles