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NCLEX: Antitubercular agents

Terms in this set (15)

Isoniazid (INH)
(tx for tuberculosis)
Pyridoxine(B6) as prophylaxsis
works in 2-3 wks of therapy
orthostatic hypotension
Give ac meals
Ethambutol (EMB)
(tx for tuberculosis)
causes optic neuritis. check visual acuity
Rifampin (RIF, Rifadin)
(tx for tuberculosis)
SE: orange urine tears, saliva
Streptomycin
Nephyotoxicity, CN VIII damage, audiograms if give long term
Para-amino- salicyclic acid (PAS)
(tx for tuberculosis)
second line agents
check for GI side effect
Pyrazinamide (PZA)
(tx for tuberculosis)
second line agents
check for liver fxn test, uric acid
Antitubercular: side effects
heptatitis
optic neuritis
seizures
peripheral neuritis
Antitubercular: Nursing consideration
used in combination (2 or more)
3 sputum cultures are negative (no longer infectious)
Tuberculosis: dx
transmitted by airborne droplets; may lie dormant for years and be activated during stress; may spread to other parts of body
Tuberculosis: risk factors
IV drug abuser
person who live in institutions
immigrants from Latin america, southeast asia, Africa
TB skin test
Mantoux Test ( PPD)
Multiple puncture test (Tine)
Mantoux test (PPD)
Given ID in the forearm (read results in 48-72 hrs
10 mm or greater induration=positive reaction. ( doesn't mean disease is present, just exposure to it or dormant (inactive TB)
> 5mm for AIDS pt=positive rxn
multiple puncture test (Tine)
read test in 48-72 hrs
vesicle formation=positive reaction
screening test only
questionable or positive rxn verified by mantoux test
TB dx procedures:
Skin testing
sputum smear of AF-bacilli
Chest x ray
QuantiFERON-TB Gold test *results with 24 hrs
on regimen for ______ months
6-9. INH, rifampin, Ethambutol and streptomycin
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