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Chapter 33 Immunity

Terms in this set (67)

Nonspecific immune response (Innate, natural immunity)
-acts as first line of defense
-offers resistance to any microbe or FOREIGN material
-lacks immunological memory (attacks a pathogen the same way every time)
Specific immune response (adaptive, specific immunity)
-resistance to a particular foreign agen
-has memory (effectiveness increases on repeated exposure to agent)
Major Components of Mammalian immune system Innate- Barriers and their effect and time
-Microbial barrier- compete for resources - 0-1 hr
-physical barrier - block entry of everything - 0-1 hr
-chemical barrier- neutralize invasion - 0-6 hr
major components of mammalian immune system (Innate) - cells and their effect
dendritic, macrophage, granulocytic, NK - 6-12 hr
- Phagocytosis
-apoptosis
major components of mammalian immune system (innate) - Processes and their effect
Opsonization, inflammation, cell communication
-recruit, combine, integrate responses
-6-72 hr
Major components of mammalian immune system (adaptive) - Cells and their effect
T cells, B cells, Dendritic, macrophage
-education, activation, tissue repair/remodel
-2 - 21 days
- 21+ days
major components of mammalian immune system (adaptive) - Chemical and their effect
Antibody, cytokine
-attack population made
-memory of population made
-21-60 days
major components of mammalian immune system (adaptive) Memory and its effect
T cells and B cells
-future response (life long immunity)
-20+ years
Direct factors in physical barriers in nonspecific resistance
-nutrition
-physiology
-fever
-age
-genetics
Indirect physical barriers in nonspecific resistance
-personal hygiene
-socioeconomic status
-living conditions
Barriers are the
first line of defense against microbes
physical barriers in nonspecific resistance - Sebaceous Glands
are antimicrobial
physical barriers in nonspecific resistance - tears
Blink
salt tears enzymes blow up cells
physical barriers in nonspecific resistance - Mucos
sticky and always moving
physical barriers in nonspecific resistance - Saliva
Lysozyme
lactoferrin
peroxidase
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