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ch 15. marijuana
Terms in this set (10)
effects of marijuana
-varried: sedation, pain relief, hallucinations.
-has its own classification
The more than 60 chemical compounds present in cannabis. One is delta-9-tetrahydrocannabinol (better known as THC)
-active cannabinoid in marijuana is responsible for psychoactive effects THC.
-within 30 mins, most is gone from the brain.
-peak physiological and CV effects occur 5 to 10 mins after smoking.
-absorbed more slowly and the liver transforms it into 11-hydroxy-delta-9-thc.
-less the reaches the brain.
-peak effects occur about 90 mins following ingestion.
mechanism of action
-THC and other cannabinoids bind to two receptors
-Cb1 and Cb2 receptors.
-Cb1 is found in the CNS and some other parts of body
-Cb2 is found in the peripheral organs and cells associated with the immune system
-THC causes increased dopamine release.
-increased hr after smoking and ingestion
-people with CVD should avoid use due to effects on hr.
-bronchodilation is seen following acute exposure.
-reddening of the eyes, dy mouth and throat
-euphoria high, mellowness, hunger, stimulaton
-verbal exchanges decrease, nonverbal increase.
-infrequent smokers experience similar but more intense effects compared with experienced smokers due to lower tolerance.
medical uses of cannabis
-appetite stimulating drugs
-can help with depression, migraines, fatigue, anxiety, anorexia, insomnia, cancer, fibromyalgia, etc.
has been shown.
-animals and humans will self administer the drug.
-oral thc doesn't have a high abuse potential due to its different time course.
-tolerance develops after regular use of high levels.
-no humans deaths reported
-panic reactions: fear or losing control and things won't return to normal, more common in less experienced users
-impairment while driving.
-chronic lung exposure drom smoking
-may contain some chemicals found in tobcacco
-reduced testosterone levels
-lower birth weight and height.
--heavy chronic users show diminished motivation, impaired ability to learn, school and family problems.
-insanity: psychotic breaks have been reported, psychotic episodes
-altered brain development.
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