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Immunology Ch. 28
Terms in this set (18)
A condition called the _________________ syndrome can be secondary to lupus and may complicate pregnancy
A diffused or homogeneous pattern in antinuclear antibody (ANA) testing characterizes
nDNA, ds-DNA, histones, ssDNA, DNP, or histones.
A major cellular immunologic feature of SLE is
hyperproduction of helper T cells, reduction of generalized suppressor T cell function, and lack of generalized suppressor T cell function.
A speckled pattern in antinuclear antibody (ANA) testing characterizes
anti-RNP and anti-Sm.
Antibodies directed against ___________ cells, including the membrane molecules that mediate their responses, are regularly detected in patients with SLE.
Laboratory features of SLE include
the presence of ANAs, decreased levels of complement, and circulating anticoagulant and immune complexes.
Many of the clinical manifestations of systemic lupus erythematosus are a consequence of
tissue damage mediated by immune complexes.
One of the most potent inducers of abnormalities and clinical manifestations of SLE is
hydralazine and procainamide
Patients with SLE characteristically manifest
dermatitis, a photosensitive facial rash, and polyarthritis
Patients with systemic lupus erythematosus exhibit serum antibodies that include
nuclear components, immunoglobulin G (IgG), and cell surface and cytoplasmic antigens.
Serologic assessment of renal disease in systemic lupus erythematosus (SLE) includes
cryoglobulin level assay.
SLE is more common in
The most common form of lupus is
The most frequent cause(s) of mortality in hospitalized patients with SLE and progressive renal involvement or CNS disease is (are)
The overall incidence of SLE has an increased frequency among
African Americans, Puerto Ricans, and native americans
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