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Lab Values and Drug Monitoring

Terms in this set (12)

POC testing
test that provides quick results at the site of patient care
therapeutic drug monitoring
obtaining drug levels or related labs to monitor for efficacy and safety
CBC (with differential)
WBC, RBC, platelets

Differential - more specific about types of WBC (neutrophils, leukocytes, monocytes, eosinophils, basophils)
average lifespan of RBC
120 days
average lifespan of platelet
7-10 days
BMP
electrolytes, renal function, glucose (Na, Cl, K, bicarb, SCr, BUN, glucose, Ca)
CMP
BMP + LFTs (AST, ALT, t. bili, t. protein)
immature RBC
reticulocyte
myelosuppression
decrease in WBC, RBC, platelets
agranulocytosis
decrease in granulocytes (basophils, eosinophils, neutrophils)

can be caused by drugs such as clozapine
critical lab
lab value that can be life threatening if not immediately fixed
therapeutic drug levels:
carbamazepine
digoxin
lithium
phenytoin/fosphenytoin
theophylline
valproic acid
vancomycin
warfarin
carbamazepine: 4-12
digoxin (HF): 0.5-0.9
(AF): 0.8-2.0
lithium: 0.6-1.2
phenytoin/fosphenytoin: 10-20
theophylline: 5-15
valproic acid: 50-100
vancomycin: 15-20 for serious infections (pneumonia, meningitis, bacteremia, endocarditis, osteomyelitis), 10-15 for less serious infections (cellulitis)
warfarin: 2-3 (unless mitral mechanical valve, then 2.5-3.5)
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