Study sets, textbooks, questions
Upgrade to remove ads
Endocrinology: Androgen Issues
Terms in this set (13)
causes of androgen deficiency?
testicular failure (primary hypogonadism)
Hypothalamic-pituitary defects (secondary hypogonadism)
which type of DM had 25% of pts with hypogonadotropic hypogonadism and 4% had hypergonadotropic hypogonadism?
Labs of primary hypogonadism
low testosterone levels with HIGH gonadotropin levels (LH, FSH)
Klinefelter's syndrome is a primary or secondary hypogonadism dx?
causes of klinefelter's syndrome?
nDue to presence of extra one or more X chromosomes, usually a 47 XXY karyotype
the following clinical findings indicate what primary hypogonadism dx?
n47 XXY karyotype
nTestosterone levels low
nSmall testicles (<2cm in diameter in non-mosaic form)
tx of hypogonadal male pt
nRestores normal male secondary sexual characteristics(beard, body hair, external genitalia)
nRestores male sexual drive
nRestores masculine somatic development (Hgb, muscle mass)
nAdministration of gradually increasing doses of testosterone is recommended for disorders in which hypogonadism occurred prior to puberty
nDaily application of transdermal testosterone patches or gel
Androgel (gel), Testim (gel)
nParenteral administration of a long-acting testosterone ester at 1-to 3- week intervals. testosterone enanthate
Or testosterone cyclopentyl propionate.
why not treat a hypogonadism male with oral testosterone?
was not ideal because all the oral preps were 17- alkyl preps of testosterone meaning each have the capacity to cause inflammation of the liver
what problems can occur in a pt with cryptochidism?
infertility and risk of cancer
(even after surgery, and the surrounding temp is now normal and not the increased temp of abdominal cavity, still have increased risk of cancer but now much easier to assess for cancer in scrotum than in abdomen)
etiologies of male infertility
secondary impairment of spermatogenesis by androgen defieincy
2. spermatogenic tubule dysfunction (y chromosome mutations, alt of temp in testes like in varicoceles and cryptochidism, and immotile cilia syndrome)
3. ejaculatory obstruction (acquired or congenital)
4. defects of androgen receptor
5. disorders of sperm transport
6. radiation, chemo agents, environmental tocins
7. androgen abuse can lead to testicular atrophy and low sperm count
tx of ED
nCorrection of underlying disorders or discontinuation of responsible medications
nOral sildenafil (Viagra) or Levitra or Cialis enhances erection after sexual stimulation with an onset of ~30-60 min.
nContraindicated in men receiving any from of nitrate therapy & should be avoided in CHF
nInjection of alprostadil into corpora cavernosa or urethra
nVacuum constriction devices
Insertion of penile prosthesis
A 55 y. o. male under treatment for hypogonadism has a routine blood test where a CBC shows a hematocrit of 52%.
androgens (testosterone) increases production of RBCs causing increased hematocrit
-stop the androgen and then start again at a smaller dose
Increased hematocrit is of concern because of what?
neuro issues like stroke
Sets with similar terms
Male Gonadal Disorders
HDFS 3040 Exam One (Roberson)
Disorders of Sexual Development and Diff…
OB/GYN review 3
Sets found in the same folder
Esophageal Disorders- Quiz
Endocrinology: Thyroid Issues
Prenatal Transmission Infections
Infectious Diarrhea- Quiz
Other sets by this creator
Environmental Emergencies- Objectives
ER Final- Toxicology
ER Final- Peds
Recommended textbook solutions
The Human Body in Health and Disease
Gary A. Thibodeau, Kevin T. Patton
Clinical Reasoning Cases in Nursing
Julie S Snyder, Mariann M Harding
Health: The Basics
Rebecca J. Donatelle
Mathematics for Health Sciences
Other Quizlet sets
American Red Cross Lifeguard Tests A
5th Grade SOL Review with Pictures
REP Unit(2) MALE GENITAL ORGANS
1 Corinthians 15 - Flashcard MC questions - Ted Hi…