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Science
Chemistry
BBL 1 - Amino Acids
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Terms in this set (28)
Amino acid structure
Alpha chiral carbon and 4 covalently bonded groups - amine group (NH4) and carboxylic acid group (COOH)
L-isomer
All alpha amino acids isomer type
Glycine
Amino acid that is not chiral
Proline
Nitrogen of this amino acid is bound to 2 alkyl groups, making it a secondary amine -> rigid structure that does not allow it to be a hydrogen bond donor (only acceptor)
Weak Bronsted-Lowry acids and bases
Amino acids acid/base properties
Protonation of amine
Conjugate acid
Deprotonation of carboxylic acid
Conjugate base
Zwitterionic
All amino acids - amino terminal and carboxylic acid terminal at neutral pH are partially charged (amine is positive, carboxylic acid is negative)
Selenocysteine
Amino acid formed on a tRNA
Keto acids
Amino acids are formed by the amination of _______
Asp and Glu
Acidic amino acids with ionized/charged R group carboxylic acids
Lys, Arg, His
Basic amino acids with positively charged R group terminal amines
Ser, Thr, Cys, Tyr, Asn and Gln
Polar R groups
Ile, Pro, Trp, Val, Leu, Ala, Gly, Met, Phe
Non-polar R groups
Ile, Leu, Val
Branched chained amino acid R groups
Phe, Trp, Tyr
Aromatic R groups
Met
-Start signal for the translation of mRNA into protein (first amino acid of the protein being formed on the ribosome)
-Adenylylated to form AdoMet from methionine and ATP
AdoMet
Methyl donor to all macromolecules (nucleic acids, proteins, lipid) through methylating enzyme
-Pathways produce cysteine through the transsulfuration pathway and polyamines through another branch
Ornithine
Intermediate of the Urea Cycle that enters the mitochondria and condenses with carbamyl phosphate to form citrulline
Citrulline
Exits the mitochondria to condense with aspartate to form argininosuccinate, that is cleaved to form arginine
Arginine
Cleaved into urea and ornithine
Desmosine
Amino acid found in the elastin protein
Selenocysteine formation
Selenide adds the seleno group to a seryl-tRNA, forming selnocystyl-tRNA, that is then added to growing peptide chain
13
Out of 20 amino acids ____ do not ionize (no pKR for the R groups)
Non-polar amino acids
Bond and exclude water from the interior of the protein - on the exterior surface of transmembrane proteins so that they can interact with non-polar fatty acids of the membrane phospholipids, anchoring the proteins into the membrane
Polar amino acids
-Found on the surface of the globular proteins so that they can interact with water (makes the proteins soluble)
-In the active site of enzymes, binding site of receptors
R group
Dictates the chemical properties of each amino individual acid
Source of amino acid precursors
-Glycolysis
-Pentose phosphate pathway
-TCA cycle
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Verified questions
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Determine the half-life of sodium-24.
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The complete expression for the decay of the radioactive hydrogen isotope tritium may be written as ${ }^3 \mathrm{H} \rightarrow{ }^3 \mathrm{He}+\mathrm{X}+\mathrm{Y}$. The symbols $\mathrm{X}$ and $\mathrm{Y}$ represent\ A. $\mathrm{X}=\mathrm{e}^{+}, \mathrm{Y}=\bar{\nu}_{\mathrm{e}}$\ B. $\mathrm{X}=\mathrm{e}^{-}, \mathrm{Y}=\nu_{\mathrm{e}}$\ C. $\mathrm{X}=\mathrm{e}^{+}, \mathrm{Y}=\nu_{\mathrm{e}}$\ D. $\mathrm{X}=\mathrm{e}^{-}, \mathrm{Y}=\bar{\nu}_{\mathrm{e}}$
engineering
The general form of the Stefan-Maxwell equation for mass transfer of species i in an n-component ideal gas mixture along the z-direction for flux is given by $$ \frac{d y_{i}}{d z}=\sum_{j=1, j \neq i}^{n} \frac{y_{i} y_{j}}{D_{i j}}\left(\nu_{j}-\nu_{i}\right) $$ Show that for a gas-phase binary mixture of species A and B, this relationship is equivalent to Fick's rate equation: $$ N_{A, z}=-c D_{A B} \frac{d y_{A}}{d z}+y_{A}\left(N_{A, z}+N_{B, z}\right) $$
physics
Boxes are transported from one location to another in a warehouse by means of a conveyor belt that moves with a constant speed of 0.50 m/s. At a certain location the conveyor belt moves for 2.0 m up an incline that makes an angle of 10° with the horizontal, then for 2.0 m horizontally, and finally for 2.0 m down an incline that makes an angle of 10° with the horizontal. Assume that a 2.0 kg box rides on the belt without slipping. At what rate is the force of the conveyor belt doing work on the box as the box moves (a) up the 10° incline, (b) horizontally, and (c) down the 10° incline?