cancer drug AEs

Which of the following cause pulmonary toxicity? (All that apply)
A. Bleomycin
B. Trastuzumab
C. Rituxumab
D. Cisplatin
Click the card to flip 👆
1 / 10
Terms in this set (10)
Which of the following cause pulmonary toxicity? (All that apply)
A. Bleomycin
B. Trastuzumab
C. Rituxumab
D. Cisplatin
(A and B) Bleomycin and Trastuzumab cause pulmonary toxicity
-Methotrexate can cause pulmonary fibrosis
Which of the following are nephrotoxic? (All that apply)
A. Methotrexate
B. Cisplatin
C. Tacrolimus
D. Sirolimus
(A, B and C) Methotrexate, Alkylating-like agents, and Calcineurin inhibitors are nephrotoxic
- Sirolimus is NOT
Which of the following are neurotoxic? (All that apply)
A. Cytarabine
B. Lomustine
C. Cisplatin
D. Imatinib
E. Paclitaxel
F. Vincristine
(All except D) Cytarabine, Nitrosurea alkylating agents, Alkylating-like agents, and Microtubule inhibitors
Which of the following are cardiotoxic? (all that apply)
A. Methotrexate
B. Dexrazoxane
C. Trastuzumab
D. Paclitaxel
(Just C) Doxorubicin, Daunorubicin, and Trastuzumab are cardiotoxic
-Tamoxifen and Raloxifene (SERMs) can cause cardio disorders or something
Which of the following may cause infusion reactions? (all that apply)
A. Cisplatin
B. Paclitaxel
C. Rituximab
D. Trastuzumab
B, C, and D
What class of drugs can cause skin toxicities like folliculitis in > 50% of patients?
Tyrosine kinase inhibitors (-tinibs and -fenibs)
Which drug is known to cause liver toxicity?
Methotrexate (antimetabolites as a class do too... but it's not bolded)
Which drug that causes alopecia was the only one bolded? (rip)
A. Antitumor antibiotics
B. Microtubule inhibitors
C. 5-fluorouracil
D. Methotrexate
C. 5-fluorouracil
-though the other options except for methotrexate also cause alopecia... it's just not bolded
Which of the following cause ototoxicity? (all that apply)
A. Paclitaxel
B. Cisplatin
C. Cytarabine
D. Cladribine
(B and C) Alylating-like agents and Cytarabine case ototoxicity
What drug causes ocular toxicity?
Cytarabine
-Tamoxifen causes ocular effects