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5 Written questions

5 Matching questions

  1. What is tx for Churg-Strauss Syndrome?
  2. How do you tx myasthenia gravis?
  3. What has asthma as its cardinal feature and the pt also has nasal polyps and allergic rhinitis. This affects small to medium sized vessels and can also be associated with tingling in extremities, can affect the lungs, etc...
  4. In myasthenia gravis what do you see with the thymus gland?
  5. What is tx for Takayasu's arteritis?
  1. a NAP: (since it improves with rest)/ otherwise CT
    Anticholinesterase drugs give symptomatic relief
    i.e. Neostigmine 15 mg qid and Pyridostigmine 60 mg qid; thymectomy; failure of above - corticosteroids
  2. b Churg-Strauss Syndrome
  3. c it is abnormal (thymoma = thymic hyperplasia)/ it has clusters of immune cells indicative of lymphoid hyperplasia/ autoimmunity and production of the acetylcholine receptor antibodies setting the stage for attack on neuromuscular transmission -> skel muscle weakness
  4. d P M & M: Prednisone 1 mg/kg/d tapered to < 20 in 8-20 wks with maintenance at 10 mg; Methotrexate 25 mg/wk and mycophenolate mofetil 1500 mg bid for those who are refractory
  5. e High dose prednisone 40-60 mg/d tapered slowly after 1 month; immunosuppressive agents

5 Multiple choice questions

  1. Giant Cell Arteritis (blindness if untreated)
  2. urgently with prednisone 60 mg/d immediately -> bx to confirm/ then low dose ASA 81 mg/d/ continue prednisone 1 month before tapering
  3. nose, soft palate, petechiae, gums, GI and CNS; good
  4. Takayasu's Arteritis
  5. crucial to prevent end-organ damage/ tightly control htn
    CAP: Cyclophosphamide and prednisone, ASA 325 mg for TIAs/ AM: Azathioprine 2 mg/kg/d for remission and methotrexate 20 mg/wk if not sign/renal dysfunction

5 True/False questions

  1. What should you screen for in pt's with polyarteritis nodosa?Hep screening since 10% associated with Hep B

          

  2. What is the hallmark in lab findings for ITP?thrombocytopenia with platelet counts less than 10,000/mcL (counts less than 5000/mcL can lead to CNS bleeding); peripheral smear, bone marrow and coagulation studies are normal

          

  3. What is in the differential diagnosis for ITP?thrombocytopenia with platelet counts less than 10,000/mcL (counts less than 5000/mcL can lead to CNS bleeding); peripheral smear, bone marrow and coagulation studies are normal

          

  4. How do you dx myasthenia gravis?NAP: (since it improves with rest)/ otherwise CT
    Anticholinesterase drugs give symptomatic relief
    i.e. Neostigmine 15 mg qid and Pyridostigmine 60 mg qid; thymectomy; failure of above - corticosteroids

          

  5. How do you treat polyarteritis nodosa?high dose corticosteroids (60 mg Prednisone daily), Methylprednisolone 1 g IV daily for 3 days if critically ill, immunosuppressive agents like Cyclophosphamide; Hep B responds to short course of prednisone + lamivudine 100 mg/d and plasmapheresis 3 wk for 6 weeks