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Hematology I Chapter 19

Terms in this set (29)

anemia of chronic inflammation
lack of accessible iron is the mechanism for iron deficiency and?
infants and young children
patients most likely to develop iron deficiency from increased need
chronic blood loss
most common cause of iron deficiency in adult males and postmenopausal females
attached to hemoglobin in the red blood cells
where is most of the iron in the body found?
stage 2 iron deficiency
the ferritin test is being used to screen for hereditay hemochromatosis. A healthy young woman has low ferritin. the most likely cause is?
free erythrocyte protoprhyrin (FEP)
the best test to distinguish iron deficiency anemia (IDA) from anemia of chronic inflammation (ACI)
young men
least likely to develop iron deficiency
red cell distribution width (RDW)
parameter of the routine CBC that is a sensitive indicator of preclinical iron deficiency
low MCV, MCH, MCHC
typical in stage 3 iron deficiency
iron deficiency from increased need and inadequate diet
what is most likely if a 10 month old child fed only cow's milk has the following results:
serum iron decreased
TIBC increased
Ferritin decreased
acute phase reactants impair iron mobilization
what is the mechanism for the anemia of chronic inflammation?
low serum iron and low TIBC
typical lab results for anemia of chronic inflammation
basophilic stippling
inclusions found in lead poisoning
interfere with heme production
how does lead exposure and the porphyrias cause anemia?
accumulated porphyrin compounds in tissue
what most of the clinical findings in the porphyrias are related to
life-long repeatd red cell transfusions
transfusion-related hemochromaatosis is seen in patients who have??
free radicals and superoxide formed from ferrous iron plus oxygen damage cell membranes
why is too much iron dangerous?
eating iron rich foods along with those high in ascorbic acid
what promotes increased iron absorption?
albumin
increased in patients with hereditary hemochromatosis
reticulocyte count
the test that rises after one successful treatment for iron deficiency
anemia absent
MCV normal
Ferritin decreased
characteristics of stage 1 iron deficiency
free erythrocyte protoporphyrin (FEP) is increased
true of stage 3 iron deficiency
fasting in the morning
when should blood for iron studies be drawn?
iron deficiency anemia
chronic blood loss leads to:
high tranferrin
what would point to iron deficiency anemia as opposed to the anemia of chronic inflammation?
inherited siderblastic anemia
ringed siderblasts are seen in?
mitochondria
ringed sideroblasts are a reflection of iron-laden......
impaired mental development may occur
why is lead poisoning of particular concern in children?
it is an acute phas protein
it is a hormone
it increases in response to increased iron stores
true of hepcidin
THIS SET IS OFTEN IN FOLDERS WITH...