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S&H: Transfusion therapy, Rxns

Terms in this set (50)

Although the optimal PCV in small animals is more than _________%, oxygen delivery in a normovolemic, resting animal can be maintained down to a PCV of _________% (although this is completely inadequate under most disease conditions)
Although the optimal PCV in SAs is more than 30%, O2 delivery in a normovolemic, resting animal can be maintained down to a PCV of 10% (inadequate under most d'se conditions)
For an anemic dog or cat, what sort of transfusion could be indicated?
RBC transfusion of some kind
-pRBCS
-FWB or stored whole blood
Animals with rapidly progressive anemia should be transfused when the PCV is approximately what?
Rapidly progressive anemia >> Transfuse when PCV 20% to 25%
What volume can canine blood donors give? Cat blood donors?
-Dogs 20 ml/kg
-Cats 10 ml/kg
Animals with peracute blood loss will not show a drop in PCV for several hours after hemorrhage. Why?
With whole blood loss, a change in PCV will not occur until there has been time for intercompartmental fluid shifts occur OR fluid therapy is instituted
T or F: In most animals with anemia secondary to acute blood loss, fluid therapy alone will restore vital organ perfusion
TRUE
(Although pRBCs should be considered in any animal with evidence of anemia-related tissue hypoxia)
Animals that require anesthesia and surgery should have a PCV of at least _______% to ensure adequate oxygen-carrying capacity during anesthesia
Animals that require anesthesia and surgery should have a PCV of at least 20% to ensure adequate oxygen-carrying capacity during anesthesia
If a patient has a coagulopathy resulting in hemorrhage (but not severely anemic at this time), what blood product may be indicated for transfusion? Why?
Fresh Frozen Plasma (FFP)
-It has all coagulation factors
If a patient has hypoalbuminemia less than 1.5 g/dL, they may benefit from a transfusion of what blood product?
FFP
What 4 things is cryoprecipitate rich in?
-vWF
-Factor 8 (VIII)
-Fibrinogen
-Fibronectin
What blood product is best to use in a thrombocytopenic patient with life-threatening hemorrhage?
pRBCs to correct the anemia
(you could use FWB, but not required)
What are blood types?
Genetic markers on erythrocyte surfaces that are species-specific and antigenic in individuals that lack the same markers
The most important canine blood type is what? Why?
DEA 1
(DEA 1 elicits are strong alloantibody response after sensitization of a DEA 1 neg dog by a DEA 1 pos transfusion >>Hemolytic transfusion rxn)
What is the universal donor type in dogs?
DEA 1 neg
T or F: Dogs cannot experience NI
FALSE
If a bitch has been previously transfused with MISMATCHED blood, she can have NI
(otherwise, no concern)
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