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TB and Mycobacterium Treatment
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Why use multi-drug therapy with active TB?
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-enhances rates of response/cure
-reduces emergence of resistance
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Terms in this set (57)
Why use multi-drug therapy with active TB?
-enhances rates of response/cure
-reduces emergence of resistance
What are methods of increasing adherence/Rx completion?
-shortest possible course of therapy
-DOT
Why do you need an adequate duration of TB therapy?
-increase cure rate
-reduce relapse
How is Isoniazid HCL used clinically?
-first line drug for active pulmonary TB
-used in combo with at least 2 other active drugs, except for when treating LTBI
What is the MOA of INH?
-pro drug that is activated by catalase peroxidase
-targets inhA gene products (cell wall my colic acid)
