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Peyer's patches are clusters of lymphoid tissue found primarily in the small intestine.


The lymphatics function to absorb the excess protein-containing interstitial fluid and return it to the bloodstream.


Lymphatic capillaries are impermeable to proteins.


Digested fats are absorbed from the intestine by the lymph capillaries.


Transporting lipids is an important function of the lymphatic system.


Because lymph vessels are very low-pressure conduits, movements of adjacent tissues are important in propelling lymph through the lymphatics.


Lymphocytes reside temporarily in lymphoid tissue, then move to other parts of the body.


All the lymphoid organs are well developed before birth.


The thymus contains T cells.


Which of the following would not be classified as a lymphatic structure?


The distal portion of the small intestine contains clumps of lymph follicles called ________.

Peyer's patches

The thymus is most active during ________.


What effect does age have on the size of the thymus?

The thymus initially increases in size and then decreases in size from adolescence through old age.

Antibodies that act against a particular foreign substance are released by ________.

plasma cells

Lymph leaves a lymph node via ________.

efferent lymphatic vessels

By secreting hormones, the thymus causes what cells to become immunocompetent?

T lymphocytes

The composition of lymph is most similar to:

interstitial fluid

Select the correct statement about lymphocytes.

B cells produce plasma cells, which secrete antibodies into the blood.

A ring of lymphoid tissue that appears as a swelling of the mucosa in the oral cavity is called a(n) ________.


The tonsils located at the base of the tongue are the ________.

lingual tonsils

Which of the following is not a normal component of lymph?

red blood cells

The mechanism of the "lethal hit" of cytotoxic T cells involves a protein called perforin.


Cellular ingestion and destruction of particulate matter is called phagocytosis.


Antibodies provide a mechanism of specific resistance.


Tolerance for self-antigens is normal.


Somatic recombination by B cells allows each B cell to form its own unique antibody genes.


Perforins are cytolytic chemicals used by NK cells.


Which of the following is characteristic of antibodies?

composed of heavy and light polypeptide chains

Which of the following is associated with passive immunity?

passage of IgG antibodies from a pregnant mother to her fetus

Which of the following is not a type of T cell?


B lymphocytes develop immunocompetence in the ________.

bone marrow

Which of the following is not a function of the inflammatory response?

replaces injured tissues with connective tissue

The system that recognizes foreign molecules and acts to immobilize, neutralize, or destroy them is the ________.

immune system

The process whereby neutrophils and other white blood cells are attracted to an inflammatory site is called ________.


B cells proliferate and differentiate into plasma cells in the:

lymph nodes

The only T cells that can directly attack and kill other cells are the ________.

cytotoxic cells

Interferons ________.

interfere with viral replication within cells

Regulatory T cells ________.

may function in preventing autoimmune reactions

The only immunoglobulin to exist as a pentamer is ________.


________ are released by activated T cells and macrophages to mobilize immune cells and attract other leukocytes into the area.


B cells respond to the initial antigen challenge (primary response) by ________.

producing progeny cells that include plasma cells and memory cells

Cancer cells and virus-infected body cells can be killed before activation of adaptive immunity by ________.

natural killer cells

Which of the following is not characteristic of the adaptive immune system?

It is specific for a given organ.

Innate (nonspecific) immune system defenses include ________.


Immunocompetence ________.

is the ability of individual cells to recognize a specific antigen by binding to it

Select the correct statement about active and passive immunity.

Active and passive humoral immunity are both mechanisms of specific immunity that use antibodies.

Antibodies are:

gamma globulin glycoproteins

Clonal selection of B cells ________.

results in the formation of plasma cells

The primary immune response ________.

has a lag period while B cells proliferate and differentiate into plasma cells

There are over ________ different types of antigen receptors.

a billion

Which of the following is true about the number of binding sites per functional antibody unit?

IgM contains 10 binding sites.

In cell-mediated immunity, the antigenic cell/molecule is destroyed by:

killer T cells

Which statement is true about T cells?

Their proliferation is enhanced by interleukins 1 and 2.

Interleukin ________ inhibits or turns down the immune response.


The most common structural class of antibody molecules is:


Complement proteins and antibodies coat a microorganism and provide binding sites, enabling macrophages and neutrophils to phagocytize the organism. This phenomenon is termed ________.


Which of the following would most likely increase a person's risk of invasion by pathogenic microges?

loss of epidermal tissure

Antibody mediated immunity is most effective against:

antigens in body fluids

Which of the following possess Class II MHC antigens?

antigen-presenting cells

Giving someone an intravenous injection of immunoglobulin would:

protect him from a specific disease by giving him passively acquired immunity.

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