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60 terms

Lymphatics & Immunity (3)

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Peyer's patches are clusters of lymphoid tissue found primarily in the small intestine.
true
The lymphatics function to absorb the excess protein-containing interstitial fluid and return it to the bloodstream.
true
Lymphatic capillaries are impermeable to proteins.
false
Digested fats are absorbed from the intestine by the lymph capillaries.
true
Transporting lipids is an important function of the lymphatic system.
true
Because lymph vessels are very low-pressure conduits, movements of adjacent tissues are important in propelling lymph through the lymphatics.
true
Lymphocytes reside temporarily in lymphoid tissue, then move to other parts of the body.
true
All the lymphoid organs are well developed before birth.
false
The thymus contains T cells.
true
Which of the following would not be classified as a lymphatic structure?
pancreas
The distal portion of the small intestine contains clumps of lymph follicles called ________.
Peyer's patches
The thymus is most active during ________.
childhood
What effect does age have on the size of the thymus?
The thymus initially increases in size and then decreases in size from adolescence through old age.
Antibodies that act against a particular foreign substance are released by ________.
plasma cells
Lymph leaves a lymph node via ________.
efferent lymphatic vessels
By secreting hormones, the thymus causes what cells to become immunocompetent?
T lymphocytes
The composition of lymph is most similar to:
interstitial fluid
Select the correct statement about lymphocytes.
B cells produce plasma cells, which secrete antibodies into the blood.
A ring of lymphoid tissue that appears as a swelling of the mucosa in the oral cavity is called a(n) ________.
tonsil
The tonsils located at the base of the tongue are the ________.
lingual tonsils
Which of the following is not a normal component of lymph?
red blood cells
The mechanism of the "lethal hit" of cytotoxic T cells involves a protein called perforin.
true
Cellular ingestion and destruction of particulate matter is called phagocytosis.
true
Antibodies provide a mechanism of specific resistance.
true
Tolerance for self-antigens is normal.
true
Somatic recombination by B cells allows each B cell to form its own unique antibody genes.
true
Perforins are cytolytic chemicals used by NK cells.
true
Which of the following is characteristic of antibodies?
composed of heavy and light polypeptide chains
Which of the following is associated with passive immunity?
passage of IgG antibodies from a pregnant mother to her fetus
Which of the following is not a type of T cell?
antigenic
B lymphocytes develop immunocompetence in the ________.
bone marrow
Which of the following is not a function of the inflammatory response?
replaces injured tissues with connective tissue
The system that recognizes foreign molecules and acts to immobilize, neutralize, or destroy them is the ________.
immune system
The process whereby neutrophils and other white blood cells are attracted to an inflammatory site is called ________.
chemotaxis
B cells proliferate and differentiate into plasma cells in the:
lymph nodes
The only T cells that can directly attack and kill other cells are the ________.
cytotoxic cells
Interferons ________.
interfere with viral replication within cells
Regulatory T cells ________.
may function in preventing autoimmune reactions
The only immunoglobulin to exist as a pentamer is ________.
IgM
________ are released by activated T cells and macrophages to mobilize immune cells and attract other leukocytes into the area.
Cytokines
B cells respond to the initial antigen challenge (primary response) by ________.
producing progeny cells that include plasma cells and memory cells
Cancer cells and virus-infected body cells can be killed before activation of adaptive immunity by ________.
natural killer cells
Which of the following is not characteristic of the adaptive immune system?
It is specific for a given organ.
Innate (nonspecific) immune system defenses include ________.
phagocytosis
Immunocompetence ________.
is the ability of individual cells to recognize a specific antigen by binding to it
Select the correct statement about active and passive immunity.
Active and passive humoral immunity are both mechanisms of specific immunity that use antibodies.
Antibodies are:
gamma globulin glycoproteins
Clonal selection of B cells ________.
results in the formation of plasma cells
The primary immune response ________.
has a lag period while B cells proliferate and differentiate into plasma cells
There are over ________ different types of antigen receptors.
a billion
Which of the following is true about the number of binding sites per functional antibody unit?
IgM contains 10 binding sites.
In cell-mediated immunity, the antigenic cell/molecule is destroyed by:
killer T cells
Which statement is true about T cells?
Their proliferation is enhanced by interleukins 1 and 2.
Interleukin ________ inhibits or turns down the immune response.
10
The most common structural class of antibody molecules is:
IgG
Complement proteins and antibodies coat a microorganism and provide binding sites, enabling macrophages and neutrophils to phagocytize the organism. This phenomenon is termed ________.
opsonization
Which of the following would most likely increase a person's risk of invasion by pathogenic microges?
loss of epidermal tissure
Antibody mediated immunity is most effective against:
antigens in body fluids
Which of the following possess Class II MHC antigens?
antigen-presenting cells
Giving someone an intravenous injection of immunoglobulin would:
protect him from a specific disease by giving him passively acquired immunity.