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Gram Negative Bacilli (Lectures 8-9)
Haemophilus, Enterobacteriaceae and Pseudomonas all possess the following characteristics: Aerobic and facultative anaerobic Gram-negative Bacilli (rod shaped)
Terms in this set (18)
cell wall polysaccharide
found within ALL gram neg bacteria, LPS on cell wall, Lipid A is toxic moiety. Fever, DIC, shock, death. Complement activation, cytokines, thrombocytopenia, leukocytosis
released into extracellular area. Enterotoxins (fluid/diarrhea), hemolysins (lyse RBC destroy leukocytes), cytotoxins (destroy cells), Type III secretion system delivers toxins), assoc. with GI infection
Escherichia coli photo
Note the gram negative bacilli in the light micrograph
Asymptomatic carriage and shedding can occur. Also note that the inoculum is high. Rose spots on the chest of a patient with typhoid fever.
These are the gram negative bacilli. Note that this pathogen requires a low inoculum (10-200) due to its acid resistance, which allows it to invade intestinal epithelial cells.
Yersinia Pestis (photo)
They develop enlarged lymphnodes (bubo) of the armpit, neck and groin. An X-ray which shows consolidation of the lungs as a result of the pneumonic plague.
Pseudomonas aeruginosa (photo)
Corneal ulcers seen in healthy patients, those with no immunosuppression, when infected.
H influenza (photo)
Note the gram negative staining bacilli. There are several types, which include Type b which can cause meningitis, sepsis, cellulitis, septic arthritis and epiglottitis. Periorbital cellulitis with purulent exudate can occur.
H parainfluenza (photo)
endocarditis is a possible complication
Francisella tularensis (photo)
ulceroglandular form which results in skin/oral lesions
Bordetella pertussis, stage 1, Catarrhal stage
At this stage, resembles a common cold. If treated, rapid recovery
Bordetella pertussis, stage 2, Paroxysmal stage
Over 1-4 wks, it resembles whooping cough. Can treat but takes a long time.
Bordetella pertussis, stage 3, Convalescent stage
Symptoms decrease within 6 months
THIS SET IS OFTEN IN FOLDERS WITH...
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