Like this study set? Create a free account to save it.

Sign up for an account

Already have a Quizlet account? .

Create an account


volume of RBC per volume of total blood

MCHC helpful in dermining

if there are a lot of spherocytes


decreased hemoglobin/hematocrit below nl range for age and gender. disease manifestation. not final diagnosis.

Sx of acute hemorrhage anemia

hypovolemia, hypotension, orthostasis, syncope, shock

Sx of tissue hypoxia

fatigue, shortness of breath, cognitive difficulties, ischemic pain

4 Response to Anemia

(1) inc HR (2) vasoconstriction (3) salt retention (3) inc 2,3 DPG (4) inc erythoproietin synthesis

3 Mechanisms of Anemia

(1) hemorrhage (2) dec RBC survival (hemolysis) (3) dec RBC proliferation

importance of reticulocyte count

if pt is making new RBCs will see high reticulocyte account (rules out dec RBC proliferation)

2 way of Anemia classification

(1) erythropoietic response (2) RBC size (MCV) and [hemoglobin]


immature RBCs relseased by bone marrow. polychromatophilic (blue)

2 measures of Reticulocytes

(1) retic index (2) absolute retic count

Retic index

retic count x Hct/ideal Hct x 0.5

Absolute retic count

retic (%) x RBC takes into account pt anemia

retic index < 2% or absolute retic count < 75,000

suggests problem with RBC production. hypoproliferative abnormality

Retic index > 2% or absolute retic count > 100,000

shows good marrow response to anemia. suggests hemorrhage or hemolysis

3 Anemias by RBC Size

(1) Microcytic (2) Macrocytic (3) Normocytic

Microcytic Anemia

low MCV (<80). refelcts hemoglobin synthesis problme.

causes of Microcytic Anemia

Thalassemia, anemia of chronic disease, iron deficiency, lead poisoning, sideroblastic anemia

Macrocytic Anemia

high MCV (>100)

Causes of Macrocytic Anemia

megalobalsic (DNA synthesis impairment) or non-megaloblastic

Normocytic Anemia

most common. marrow isnt working well or mixed or acute problem. ex acute blood loss.

2 approaches to anemia treatment

(1) treat underlying caues (2) transfusion

3 general indications for RBC transfusion

(1) cardiovascular compromise (2) hypoproliferative anemia w/ no/long recovery (3) surgery

Please allow access to your computer’s microphone to use Voice Recording.

Having trouble? Click here for help.

We can’t access your microphone!

Click the icon above to update your browser permissions and try again


Reload the page to try again!


Press Cmd-0 to reset your zoom

Press Ctrl-0 to reset your zoom

It looks like your browser might be zoomed in or out. Your browser needs to be zoomed to a normal size to record audio.

Please upgrade Flash or install Chrome
to use Voice Recording.

For more help, see our troubleshooting page.

Your microphone is muted

For help fixing this issue, see this FAQ.

Star this term

You can study starred terms together

Voice Recording