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Pathophysiology Exam 2
Terms in this set (30)
What are the most abundant cells of the blood, responsible for tissue oxygenation?
erythrocytes (RBC); 99%; 100-120 day life cycle
What are the least abundant cells of the blood, responsible for defense against infection and removal of debris; act in tissue, but transported in circulation, and are classified by structure: granulocytes and agranulocytes?
leukocytes (WBC); less than 1%
What is made of 91% of plasma?
What are the 4 proteins?
What is albumin?
function as carriers and control the plasma oncotic pressure
What are globulins?
carrier proteins and immunoglobulins
What is fibrinogen?
What is prothrombin?
also part of coagulation
What are solutes?
What is the plasma made of?
water, proteins, other solutes
What are the formed elements?
erythrocytes, leukocytes, platelets
What percent of the body is made of platelets?
less than 1%
What are the 4 functions of granulocytes?
membrane-bound granules in their cytoplasm
granules contain enzymes capable of destroying microorganisms
inflammatory and immune functions
capable of ameboid movement
What are the 3 components of granulocytes?
neutrophils, eosinophils, and basophils
What are neutrophils?
polymorphonuclear neutrophil (PMN)
phagocytes in early inflammation
What are eosinophils?
ingest antigen-antibody complexes
induced by IgE hypersensitivity
increase in parasitic infections
What are basophils?
structurally and functionally similar to mast cells
What are agranulocytes made of ?
lymphocytes and monocytes
What is a monocyte?
develops in the bone marrow and goes into the bloodstream
once mature, they make up the mononuclear phagocyte system (MPS), which ingests and destroys any unwanted material
What is a lymphocyte?
mature to T cells, B cells, and plasma cells
lives in lymphoid tissue
natural killer (NK) cells
What are platelets?
irregularly shaped cell cytoplasmic fragments
formed in bone marrow
essential for blood coagulation and control of bleeding
What are the two lymphoid organs we discuss in class?
spleen and lymph nodes
What is the largest lymphoid organ
What is the function of the spleen?
intimates immune response
destroys aged cells
not necessary for life
What occurs after splenectomy?
leukocytosis (white cell count is higher in those w/o a spleen)
What is a lymph node?
drains into the venous system (superior vena cava).. which delivers deoxygenated blood to the heart
structurally part of the lymphatic system
functionally part of hematologic and immune systems
Which marrow is active?
Which marrow is inactive?
What is the function of bone marrow?
What are multipotent stem cells?
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