ajcc staging part 3

what defines a T1 skin cancer2 cm or less with less than 2 high risk featuresa skin cancer that is greater than 2 cm OR any size with 2 or more high risk features is what T stageT2a skin tumor with invasion of maxilla, mandible, orbit, or temporal bone is what T stageT3a skin tumor with invasion of the skeleton or perineural invasion of skull base is what T stageT4what is merkel cell carcinomarare and aggressive primary cutaneous neuroendocrine carcinomamelanoma 1.0 mm or less in thickness is what T stageT1melanoma 1.01-2.0 mm is what T stageT2melanoma 2.01 to 4.0 mm is what T stageT3melanoma more than 4.0 mm is what T stageT4what stage would an ulcerated melanoma be?T#bwhat stage would a melanoma without ulceration be?T#ain breast cancer what constitutes chest wall involvementribs, intercostal muscles and serratus anterior (NOT pectoral)what are the most common sites of distant mets from breast cancerone, lung, brain, and livera breast tumor 0.1-0.5 cm in greatest dimension is what T stageT1aa breast tumor 0.5-1.0 cm in greast dimension is what T stageT1ba breast tumor 1.0 cm to 2.0 cm is what T stageT1ca breast tumor between 2.0-5.0 cm is what T stageT2a breast tumor greater than 5 cm is what T stageT3a breast tumor of any size with extension to the chest wall is what T stageT4aa breast tumor with ulceration or ipsilateral satellite nodules, edema (peau d'orange) of skin that does NOT meet criteria for inflammatory carcinoma is what T stageT4ba breast tumor meeting criteria for both T4a and T4b is what T stageT4cinflammatory breast carcinoma is what T stageT4d

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Distinguish catabolism from anabolism?

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Reconsider the above problem. In order to drain the tank faster, a pump is installed near the tank exit as in the figure. Find how much pump power input is necessary to establish an average water velocity of $4 \mathrm{~m} / \mathrm{s}$ when the tank is full at $z=2 \mathrm{~m}$ . Also, assuming the discharge velocity to remain constant, find the time required to drain the tank. Someone suggests that it makes no difference whether the pump is located at the beginning or at the end of the pipe, and that the performance will be the same in either case, but another person argues that placing the pump near the end of the pipe may cause cavitation. The water temperature is $30^{\circ} \mathrm{C}$ , so the water vapor pressure is $P_v=4.246\ \mathrm{kPa}=0.43 \mathrm{~m} \mathrm{H}_2 \mathrm{O}$ , and the system is located at sea level. Investigate if there is the possibility of cavitation and if we should be concerned about the location of the pump.

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chemistry

Consider the chlorination of (S)-2 -chloropentane at C4. (a) Write structural formulas for the products, showing three dimensions at all chirality centers. Give each its proper (R, S) designation. (b) What is the stercoisomeric relationship between these products? (c) Are both products chiral? (d) Are both optically active? (e) Could the products be separated by conventional means? (f) What other dichloropentanes would be obtained by chlorination of (S)-2-chloropentane? (g) Which of these are optically active?

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engineering

An insulated 0.15-m^3 tank contain helium at 3 MPa and 130 $^\circ{}$ C. A valve is now opened, allowing some helium to escape. The valve is closed when one-half of the initial mass has escaped. Determine the final temperature and pressure in the tank. Answers: 257 K, 956 kPa