-fever, petechial rash (red dots), severe headache, photophobia, stiff neck, positive Brudzinki sign (lift the head up cause the leg come up and fall down), nuchal igidity, positive kernig sign (neck/back pain if bring the leg/knee up), decreased LOC, hemiparesis, hemiplegia, and tachycardia. Cushing disease is excess glucocorticoid and mineralocorticoid (aldosterone) which affects carb, fat, and protein metabolism. It also effects carbohydrate and metabolism causes the blood glucose to elevate.
S/S: Buffalo hump, Moon face, Hyperglycemia, Central obesity, Purple striae, Increased cortisol and aldosterone, K+ loss/ hypokalemia, Na+ and H2O retention caused HTN, Suppression of the immune system. Metabolic alkalosis