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Antiplatelets
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Terms in this set (7)
List the medications under platelets:
-aspirin
-clopidogrel
What is the action of aspirin?
-irreversible inhibition of platelet aggregation for 8 days
-due to to inhibition of COX 1, there is protection against MI and stroke with daily dosing
-Very effective for inflammatory conditions
What are the side effects of aspirin?
-common with long-term high dose: GI upset, GI bleeding, prolonged bleeding time, renal impairment
-Salicylism (aspirin levels above therapeutic range): tinnitus, sweating, headache, dizziness
What are the nursing considerations for aspirin?
-use with caution with anticoagulants, glucocorticoids, alcohol, and vaccines
What is the action of clopidogrel?
-irreversible inhibition of platelet aggregation for 7-10 days
-Prevents the stenosis of coronary artery stents
-prevents MI, ischemic stroke, and other vascular events
-can be combined with aspirin for greater effectiveness
What are the side effects of clopidogrel?
-bleeding (less risk than aspirin)
-PPIs may reduce the effectiveness
What is the nursing consideration of clopidogrel?
-instruct pt to look for signs of bleeding
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