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Chapter 5 : Synaptic transmission
Terms in this set (23)
Identify the neuroscientists who first proved the existence of electrical synapses. Choose the correct option.
Edwin Furshpan and David Potter
What types of cells can a neuron communicate with at a synapse? Choose the correct option.
Another neuron, muscle cell, or glandular cell
What is the function of a gap junction between neurons? Choose the correct option.
Electrical synapse between the neurons
What is the other name for dense-core vesicles? Choose the correct option.
Why are neuromuscular junctions such reliable synapses? Choose the correct option.
They are almost fail-safe when the synapse is large.
What are transporters? What is their role? Choose the correct option.
Special proteins embedded in the vesicle membrane; responsible for concentrating neurotransmitters inside the vesicle
Which of the following channels in the active zones of the synaptic terminal open when the membrane depolarizes and causes the release of synaptic vesicles? Choose the correct option.
Voltage-gated calcium channels
Under what conditions are peptide neurotransmitters generally released from the synaptic terminal? Choose the correct option.
Only with high-frequency trains of action potentials
What are second messengers? Choose the correct option.
Molecules that activate additional enzymes in the cytosol
How are released neurotransmitters cleared from the synaptic cleft? Choose the correct option.
Enzymatic destruction and diffusion
How do nerve gases interfere with synaptic transmission at the neuromuscular junction? Choose the correct option.
By inhibiting the enzyme AChE
What is synaptic integration? Choose the correct option.
A process by which multiple synaptic potentials combine within one postsynaptic neuron
Quantal analysis shows that a single action potential at the neuromuscular junction causes an EPSP of 40 mV or more, compared to only a few tenths of a millivolt at many CNS synapses. What accounts for this difference? Choose the correct option.
A larger number of synaptic vesicles releasing neurotransmitter at the neuromuscular junction compared with CNS synapses
What is the effect of activating G-protein-coupled neurotransmitter receptors? Choose the correct option.
Activate effector proteins such as ion channels or those that synthesize second messengers
Protein phosphorylation can change the conformation of a protein, thereby changing its activity.True or false?
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