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Amino Acid Synthesis
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Synthesis by amidination (glutamine): Called amidination rather than ? (transamination), because amino group is added to the ? group ("on the top" of glutamate and aspartate):
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amination
carboxy
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Terms in this set (70)
Synthesis by amidination (glutamine): Called amidination rather than ? (transamination), because amino group is added to the ? group ("on the top" of glutamate and aspartate):
amination
carboxy
Amino acids are synthesized from glycolysis and TCA intermediates: an overview: Plants and microorganisms can produce all 20 ? acids, which can be found in proteins
amino
Amino acids are synthesized from glycolysis and TCA intermediates: an overview: Humans can synthesize only 11 of so-called NON-ESSENTIAL ?
AAs (amino acids)
Amino acids are synthesized from glycolysis and TCA intermediates: an overview: For these, nitrogen is derived from either ? or ?
Glu
Gln
Amino acids are synthesized from glycolysis and TCA intermediates: an overview: The remaining AAs are ? and have to be obtained from dietary sources
ESSENTIAL
Synthesis by amidination (glutamine): glutamate + NH4+ + ATP → ? + ADP
glutamine
Rule of thumb: Simple ? amino acids can be produced in one/few steps
glucogenic
Rule of thumb: Branched chain & aromatic AAs are "too difficult to ?" (exception - ?)
synthesize
tyrosine
Rule of thumb: *? is conditionally essential = essential in young, growing organismbut not in adults (can be produced in the urea cycle, but not in sufficient quantities)
Arginine
Synthesis by transamination:3 glucogenic amino acids and related carbon skeletons: ? carbons, Alanine <--→ Pyruvate (transamination: enzyme?; co-factor?)
3