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SGU Histo - Connective Tissue I
SGU SOM Term 1
Terms in this set (32)
List the 3 main components of connective tissue.
Cells, Ground Substance, Tissue Fluid.
What are 4 major functions of connective tissue?
Support, repair, immune defense, nutrition storage and transport (ie: blood and adipose tissue)
True or false? Connective tissue is highly vascular.
Parenchyma refers to tissues which are functional units, whereas connective tissue is given the term _____
List the types of cells you would expect to find in connective tissue
Fibroblasts, adipose, macrophages, mast cells... And the following transient residents: Lymphocytes, neutrophils, basophils, eosinophils, plasma cells.
What is the most common cell in connective tissue and what is its function?
Fibroblasts, produces fibres and ground substance.
Collagen stains _______ with H&E
Describe unilocular adipocytes
White fat, large fat droplet, nucleus pushed towards membrane.
What type of cells is responsible for heat production, what are their main characteristics?
Multilocular adipocytes. Lots of mitochondria (this is why they are known as brown fat), multiple cytoplasmic lipid droplets.
Do adipocytes receive lots of blood?
Yes, connective tissue is usually vascular. Blood vessels in close proximity means energy stored in these cells can be used more quickly.
What is the function of macrophages?
Phagocytize foreign matter into intracellular vesicle's, which fuse with lysosomes to be broken down into small peptide fragements. The fragments bind Major histocompatibility complex (a recptor), and the entire vesicle fuses with the membrane thus presenting the antigens to T-Cells.
What compounds related to immune function do macrophages produce?
Do mast cells in bone marrow have granules?
No, they only have granules once they reach connective tissue.
What is within mast cell granules?
Heparin, histamine, chemotactic mediators for initiating immune response. Leukotrienes (vasoactive). The granules are secreted after the cell detects an antigen.
What are the 2 types of lymphocytes?
B and T cells
What type of cell becomes a plasma cell upon activation?
What is the function of T cells?
To present interleukins to B cells and allow them to differentiate into plasma cells.
Where would you expect plasma cells production to be prominent?
In canals such as the esophagus, respiratory system, or anywhere where increased immune protection is needed.
What is the function of plasma cells?
To produce antibodies to bind a specific antigen, each plasma cell produces only one class of immunoglobulins.
What is the purpose of eosinophils?
To phagocytize the antigen antibody complex, and to kill parasites.
The larger the number assigned to a type of collagen, the more ______ and ______ it is
Brached and fibrous
Type I collagen is predominantly found in ______
Type II collagen is found in ______
Hyaline and elastic cartilage.
Type III collagen is found in _______ and can be described as...
Reticular lamina as part of reticular fibres, it is short thin and branching.
Type IV collagen is a component of the ______
Type V collagen is found....
everywhere as structural meshwork
What is the importance of reticular fibres (type III collagen)?
They are found in organs where volume needs to change and are the first type of collagen produced during wound healing.
Where would you expect to find elastic fibres?
Vocal ligament, arteries, elastic cartilage, bronchi, anything that needs to stretch.
What is elastic fibre composed of?
Fibrillin and elastin
Does collagen self-assemble?
Does elastin self-assemble?
No, microfibrils are required for the formation of elastic fibres. If absent elastin will form sheets instead.
Why are elastic fibres interwoven with collagen?
To limit distensibility to prevent tearing and excessive stretching.
THIS SET IS OFTEN IN FOLDERS WITH...
SGU Histo - Blood
SGU Histo - Epithelial Tissue I & II
SGU Histology Pre Unified
SGU HISTOLOGY WEEK 1
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