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SGU Histo - Connective Tissue II

Terms in this set (58)

What are the functions of ground substance?
Lubricant, adhesive, physical barrier, tensile strength
Where are glycosaminoglycans found in ground substance?
Attached to the core protein as a bottle brush like structure (Hyaluronan, chondroitin-4-sulphate, chondroitin-6-sulphate, heparin sulphate, keratan sulphate).
The core protein carrying the glycosaminoglycans is collectively known as a _______
proteoglycan
The proteoglycan is attached to a larger core protein, _________
Hyaluronan molecule
Collectively, the hyaluronan core protein and the attached proteoglycans are known as a ________
proteoglycan aggregate.
The red things connected to the, blue thing. The blue things connected to my, ________.
Wristwatch
Chondritin-4-sulphate is a _________
glycosaminoglycan
Chondritiin-6-sulphate is attached to _________
Core protein, it is a glycosaminoglycan
Heparan sulphate is a ______________
glycosaminoglycan
Keratan sulphate is a _________
glycosaminoglycan
Hyaluronan forms what important ground substance structure?
The core protein of a proteoglycan aggregate
List 4 proteoglycans
Aggrecan, decorin, versican, syndecan
Syndecan is a
Proteoglycan
Syndecan is responsible for
Hydration of ECM of cartilage
Decorin is a
Proteoglycan
Decorin is involved in
Collagen fibrillogenesis (helps orient fibres by attaching them to one another)
Versican is a
Proteoglycan
Versican is responsible for
cell-cell and cell-ECM interactions
Syndecan is a
Proteoglycan
Syndecan is responsible for
Binding collagen, and some other proteins (ie: heparin).
A proteocglycan is attached to
Hyaluronan (core protein)
List 3 multi-adhesive glycoproteins
Laminin, fibronectin, osteopontin.
Where can the multiadhesive glycoprotein laminin be found?
Basement membrane
What's a good stain for seeing glycoproteins and proteoglycans?
Period Acid Schiff (PAS)
What condition is characterized by abnormal amount of fluid leaving the blood stream and entering the tissue fluid?
Edema
What class do these two connective tissues fall into: Mesenchyme, Mucous connective tissue
Embryonic connective tissue
What class do the following connective tissues fall into: Loose connective tissue, Dense connective tissue
Connective tissue proper
What do mesenchymal (embryonic) connective tissue cells do?
Synthesize collagen until they are ready to differentiate
What type of connective tissue has few cells and few fibres? Where can it be found
Mucous connective tissue. Umbilical cord (Wharton's jelly), cardiac jelly, vitreous humor in eye.
What is the significance of mucous connective tissue in the umbilical cord?
prevents knotting.
What type of connective tissue is predominantly composed of cells, is flexible, and rich is blood supply?
Loose connective tissue
Is loose connective tissue resistant to stress?
No
What is connective tissue of the mucous membranes of respiratory and alimentary systems called?
Lamina propria
Where can you find Lamina propria (type of loose connective tissue)
Mucous membrane of respiratory and alimentary systems.
What 2 types of connective tissues have few cells and many fibres?
Dense regular, and dense irregular
What type of connective tissue is found in the Dermis of the skin?
Dense irregular
What type of connective tissue is found in capsules of organs?
Dense irregular
What type of connective tissue is found in the submucosa of the gastro-intestinal tract?
Dense irregular
What is the purpose of irregular fibre arrangement in dense irregular connective tissue?
To withstand stress from many directions
Where can dense irregular connective tissue be found?
Dermis of skin, capsule of organs, submucosa of GIT.
What type of connective tissue can be found in Tendons?
Dense regular
What type of connective tissue can be found in ligaments?
Dense regular
What type of connective tissue can be found in apneurosis?
Dense regular
What is the purpose of having regularly arranged fibres in dense regular connective tissue?
Impart tensile strength.
Where can dense regular connective tissue be found?
Ligaments, tendons, apeurosis.
Epitendium refers to connective tissue that...
Covers an entire tendon
Peritendium refers to connective tissue that...
Covers a group of cells
Endotendium refers to connective tissue that...
Covers a cell
Tendinocytes are
Fibrocytes of tendons
Reticular connective tissue can be recognized by its...
Short branching fibres
Reticular fibres are made of...
Type III collagen
Which type of tissue forms the framework for myeloid (bone marrow), and lymphoid (lymph nodes, spleen) organs?
Reticular connective tissue
What are reticular cells?
Modified fibroblasts that secrete reticular fibres
What type of connective tissue is found in ligamentum flavum?
Elastic
What type of connective tissue is found in the vocal ligament?
Elastic
What type of connective tissue is found in the suspensory ligament of the penis?
Elastic
Where can you find elastic connective tissue?
Vocal ligament, ligamentum flavum, suspensory ligament of the penis.
Is blood connective tissue?
Yes
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