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Diseases and Biosecurity (AVS 2040)
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Terms in this set (49)
Equine Encephalitis
- sleeping sickness
- mosquito-borne (birds are vectors)
- incubation period 5-15 days
- 3 strains (EEE, WEE, VEE)
Symptoms of Equine Encephalitis
- fever
- lethargy
- anorexia
- neurological symptoms 5 d after exposure
- impaired vision
- ataxia, convulsions, death 2-3 d after neuro
WEE - somnolence - sleeping for long periods of time
West Nile
- worldwide distribution, endemic to all states
- mosquito-borne
- birds are reservoirs (vectors)
- zoonotic
Fatality of West Nile
30-40%
60-80% if unable to rise
Fatality of EEE
90%
Symptoms of West Nile
- fever
- anorexia
- ataxia
- circling, hind limb weakness, recumbency, inability of stand
- partial paralysis (limbs, lips)
- teeth grinding
- colic
Equine Herpes Virus (EHV)
- aka Rhinopneumonitis
- 9 diff. strains
- most concerned with EHV-1 and EHV-4 in US
- direct contact, indirect contact (up to 1 mo), airborne
- highly contagious
- supportive care, isolation for 28 d
EHV-1
4 diff. manifestations
- neurological
- respiratory
- abortion
- neonatal death
EHV-4
- mostly upper respiratory and mostly effects young horses
- rarely associated with abortions or neurological manifestations
Symptoms of EHV
- high fever (2 phases)
- nasal discharge
- lethargy
- anorexia
- neurological symptoms
- loss of tail bone
- urine dribbling
Equine Influenza (Flu)
- Influenza A - H3N8 is the main subtype
- highly contagious upper respiratory disease
- incubation period 1-3 days
- airborne, direct/indirect contact
- low mortality - most return to work within 3-6 wks
- pneumonia can develop
- supportive care, isolation, rest
Symptoms of Equine Influenza
- sudden high fever (up to 106)
- coughing
- clear, runny discharge
- swollen lymph nodes
Tetanus
- from clostridium tetani in the soil
- most likely affected are horses with puncture wounds or deep lacerations, mare with retained placentas, foals via the umbilical stump
- 80% mortality
- incubation period 8-14 d
Symptoms of Tetanus
- stiffness and muscle spasms
- difficult chewing/swallowing
- erect ears, tail stiff, and extended
- "sawhorse" stance
- high fever in severe cases
Treatment for Tetanus
- if caught early -> antitoxin
- antibiotics
- supportive care
Rabies
- from saliva of infected animals
- relatively uncommon
- long incubation period (2-6 wks)
- death within 5-7 d after onset of clinical signs
What is the only way to diagnose rabies?
Examination of brain tissue post-mortem
Symptoms of Rabies
- highly variable
- depression and/or manic behavior
- lameness
- anorexia
- difficulty urinating
- persistent erection
- neurological
Treatment for rabies
- no treatment
- isolation
- humane euthanasia
Vaccine Schedule - WEE/EEE
once or twice per year (S & F)
Vaccine Schedule - W.Nile
Once per year (up to 4x/year)
- spring if once
Vaccine Schedule - Rhino (EHV-1 and EHV-4)
twice per year (S & F)
Vaccine Schedule - Influenza
Twice per year (S & F)
Vaccine Schedule - Rabies
Once per year (Spring)
Vaccine Schedule - Tetanus
once per year (if wound sustained or surgery more that 6 months from vaccine -> revaccinate)
What does the Coggins Test test for?
Equine Infectious Anemia (EIA) aka swamp fever
How often is a Coggins Test done?
once a year or when ownership is changed
Treatment of EIA
- RNA virus, rapidly mutates so no vaccine
- positive horses must be euthanized or permanently quarantined
Symptoms of EIA
- transient fever
- progressive weakness/depression
- weight loss
- disorientation
- some may not show symptoms and be carriers of the disease
Strangles
aka Equine Distemper
- upper respiratory infection caused by streptococcus equi
- highly contagious
- natural immunity after exposure
- vaccine available
Symptoms of Strangles
- fever
- nasal discharge (thick, purulent)
- swelling of submandibular lymph nodes -> abscess of those lymph nodes
Equine Protozoal Myeloencephalitis (EPM)
- caused by protozoa
- carried by opossums -> contaminate feed/water
- extremely long incubation period (could be years, stress can cause it to flare up)
- if infect, protozoa take up in brain/spinal cord from digestive tract
Symptoms of EPM
- loss of coordination/ataxia/paralysis
- facial paralysis
- head tilting
- abnormal sweating
- seizures
Treatment of EPM
- diagnose using spinal fluid
- treat with anti-protozoal drugs ($$$) - variable outcomes
Potomac Horse Fever
- bacteria was found primarily in the Potomac River Area (VD, MD)
- bacteria infects snails -> water loving insects -> larva ingested by horse
- bacteria attacks intestines (colic like symptoms)
- vaccine available (annually or biannually)
Mortality rate of Potomac Horse Fever
50% mortality
- 25-30% of survivors have chronic laminitis
Symptoms of Potomac Horse Fever
- fever
- lethargy/depression
- loss of appetite
- colic like symptoms
- diarrhea
- abortion
Vesicular Stomatitis
- viral disease spread through direct contact with saliva or ruptured blisters
- sporadic disease, re-emerging
- vaccine available during outbreaks
Symptoms of Vesicular Stomatitis
- lesions on tongue, gums, teats, and coronet bands
- effects horses, cattle, and swine
- lesions in mouth will cause drooling, chomping, rubbing mouth
- lesions on coronet can cause lameness
Treatment for Vesicular Stomatitis
- supportive treatment
- antibiotics for secondary infection
Pigeon Fever
- soil-inhabiting bacteria releases toxin that causes severe inflammation and local tissue damage
- enters through small wounds and causes external abscesses mostly commonly on the the pectoral and barrel regions
Treatment of Pigeon Fever
- abscesses should be lanced and drained
- infected horses isolated during active draining
- daily cleaning/flushing of abscesses with dilute betadine
Equine Viral Arteritis (EVA)
- caused by Equine Arteritis Virus (EAV)
- transmitted through respiratory secretions, indirect contact, shed in semen, and in utero
Do stallions with EVA remain carriers?
Yes
Vaccine Schedule for EVA
- Breeding stallions vaccinate annually
- Vaccinate mares 3 weeks prior to breeding to a carrier stallion
What is the problem with EVA?
Cannon distinguish carriers from vaccinates
- must keep record of vaccination
Symptoms of EVA
- depression
- anorexia
- conjunctivitis
- nasal discharge
- skin rash
- abortion
- pneumonia and death in foals
- not typically fatal except young foals
Should you vaccinate a horse with a fever?
No! This is a reason vets require a brief exam prior to vaccination
Can modified-life virus vaccines be given to pregnant mares?
No! While most vaccines are killed make sure to pay attention to what you're giving when vaccinating broodmares.
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Acetylene gas and x times theoretical air (x >1) at room temperature and 500 kPa are burned at constant pressure in an adiabatic flow process. The flame temperature is 2600 K, and the combustion products are assumed to consist of N2, O2, CO2, H2O, CO, and NO. Determine the value of x.
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One method for determining the purity of aspirin (empirical formula $\mathrm { C } _ { 9 } \mathrm { H } _ { 8 } \mathrm { O } _ { 4 } )$ is to hydrolyze it with NaOH solution and then to titrate the remaining NaOH. The reaction of aspirin with NaOH is as follows: $$ \begin{array} { l } { \mathrm { C } _ { 9 } \mathrm { H } _ { \mathrm { 8 } } \mathrm { O } _ { 4 } ( s ) + 2 \mathrm { OH } ^ { - } ( a q ) } \\ { \text { Aspirin } } \end{array} \frac { \text { Boil } } { 10 \mathrm { min } }\rightarrow \begin{array} { l } { \mathrm { C } - \mathrm { H } _ { 5 } \mathrm { O } _ { 3 } ( a q ) + } \\ { \text { Salicylate ion } } \end{array} \begin{array} { l } { \mathrm { C } _ { 2 } \mathrm { H } _ { 3 } \mathrm { O } _ { 2 } - ( a q ) + \mathrm { H } _ { 2 } \mathrm { O } ( l ) } \\ { \text { Acetate ion } } \end{array} $$ A sample of aspirin with a mass of 1.427 g was boiled in 50.00 mL of 0.500 M NaOH. After the solution was cooled, it took 31.92 mL of 0.289 M HCl to titrate the excess NaOH. Calculate the purity of the aspirin. What indicator should be used for this titration? Why?
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Find the energy loss when oil with a specific gravity of $0.87$ flows from a $4$ -in the pipe to a $2$-in pipe through a sudden contraction if the velocity of flow in the larger pipe is $4.0\ \mathrm{ft} / \mathrm{s}$.
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