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Pediatric Hematology/ Immunology
Terms in this set (62)
4.5 - 5.5
35% - 45%
31% - 37%
Normal reticulocyte count
0.5% - 1.5%
`Normal WBC count
4.5 - 13.5
Normal neutrophil count
54% - 62%; 3-5.8
Normal neutrophil bands
3% - 5%; 0.15-0.4
1% - 3%; 0.05 - 0.25
0.075%; 0.015 - 0.03
25% - 33%; 1.5 - 3
3% - 7%
Normal platelet count
RBC count is a good reflection of
bone marrow function
MCV measures the
mean volume of a single RBC
MCH measures the
mean quantity of a single RBC
not dependent on accurate RBC counts
MCHC measures the
average concentration of hemoglobin a single RBC
Decreased reticulocyte count indicates
depressed bone marrow function
Increased reticulocyte count indicates
erythrogenesis in response to some stimulus
number of mature RBC's produced by bone marrow
Reticulocyte count can indirectly estimate the presence of
hypo chromic anemia
Elevated reticulocyte count is common in patients with
chronic hemolytic anemia
Eosinophils are increased in
allergic reactions, parasitic infections, certain neoplasms, and other diseases.
Neutrophils are increased in
histamine, heparin, and serotonin
Basophils are responsible for
increased blood flow to injured tissues and preventing clotting
Lymphocytes are responsible for
developing antibodies and delayed hypersensitivity
Monocytes are responsible for
early inflammatory reactions
the body's capability to fight bacterial infections
Anisocytosis refers to
size of RBC
Polykilocytosis refers to
shape of RBC's
where is majority of the iron stored in fetuses?
the circulating erythrocytes of the fetus
where is the rest of iron stored in the fetus if not in circulation?
liver, spleen, and bone marrow
why are babies with iron deficiency anemia typically overweight?
excessive milk ingestion
infants 12 months or younger should not be drinking cow's milk because it
increases risk for GI blood loss
A guaiac test is a
test occult blood for intermittent blood loss
What helps facilitate the absorption of iron?
ascorbic acid or vitamin c
Regional lymphadenopathy, transient arthralgia's or serious allergic reactions are associated with
parenteral iron supplement administration
Parenteral iron is saved for those with
iron malabsorption, chronic hemoglobinuria, and intolerance to oral iron
Packed RBC's are preferred over whole blood in transfusions for anemic patients because it
minimizes the chance for circulatory overload
A citrus or fruit juice is recommended to take with
What is an indication of adequate iron supplement intake?
green or black tarry stools
liquid iron supplement commonly causes
Interventions to prevent staining of teeth with liquid iron are
use a straw or syringe to administer and brush teeth after taking
what method is used for IM iron dextran injection?
z track method
what is the major risk with IV iron administration?
For a normal full term infant, at what age should they start taking iron supplements?
For a preterm or low birth weight baby, what age should they begin taking iron supplements?
What is the first solid food a child begins to eat at 6 months of age?
iron fortified cereals
SCA is the
homozygous form in which valine is substituted for glutamic acid at the 6th position of the beta chain
Sickle cell- C disease is the
heterozygous variant characterized by the presence of both HgbS and HgbC in which lysine is substituted for glutamic acid at the sixth position of the beta chain
The beta plus form of sickle thalassemia is a form where
some normal HbA is produced.
The beta zero form of sickle thalassemia occurs when
there is no ability to produce HbA
SCA is most common in which ethnic group?
SCD is one of the most common genetic diseases in which gorup?
What is the theory behind high incidence of sickle cell trait in West Africans?
it is the result of selective protection afforded trait carriers against one type of malaria
What defines an individual with sickle cell trait?
heterozygous with normal HbA and abnormal HbS
What factor if predominately pronounced, does not include sickling?
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