Oral Pathology Chp. 3

The immune system usually defends the body against foreign substances that are called:
Memory is an important function of the immune system because:
It allows faster future immune response
Immunization with a vaccine works by:
Producing active acquired immunity
A B lymphocyte is a cell in the immune system that:
Is derived form a precurser stem cell.
A macrophage is a cell in the immune system that:
Can be activated by lymphokines
Which statement of NK cell is true:
-NK cells do not circulate.
-NK cells secrete antibodies.
-NK cells are part of the body's innate immunity.
-NK cells are T lymphocytes.
NK cells are part of the body's innate immunity
In which type of immunopathologic disease are the cells of the body no longer tolerated and treated by the immune system as antigens?
Autoimmune disease
During the anaphylatic type of hypersensitivity reaction, the plasma cells:
produce antibody called Ig E
Which type of hypersensitivity reaction involves activated complement?
Type II
What type of lymphocyte matures in the thymus, produces lyphokines, and can increase or suppress the humoral immune response?
T lymphocyte
The immune system anitbodies are proteins that are:
Also called immunoglobulins
Which type of immunologic disease involves a decreased number or activity of lymphoid cells?
The humoral immune response involves the productions of:
The measurement of a specific antibody level in the blood is called:
Which type of immunity may be provided immediately to dental personnel after needlestick accidents?
Acquired passive immunity
Which of the following situations would result in the least risk of drug allergy?
-Application of topical medication
-Presence of infection
-Presence of multiple allergies
-Use with children
Use with children
Which of the following is involved in the regulation of both humoral and cell-mediated immunity?
-Humoral immunity
-Cell-mediated immunity
-Innate immunity
-The bone marrow
Cell-mediated immunity
Which of the following is involved in the communication between lymphocytes within the immune system?
All of the following are examples of hypersensitivity reactions except:
-Systemic lupus erthematosus
-Contact mucositis.
Systemic lupus erythematosus
Reiter synderome is:
An immunologic disorder
Which one of the following types of hypersensitivity reactions is referred to as delayed hypersensitivity?
-Type I
-Type II
-Type III
-Type IV
Type IV
The "target lesion" on the skin is associated with which of the following diseases?
-Behcet syndrome
-Systemic lupus erythmeatosus
-Lichen planus
-Erythema multiforme
Erythema multiform
Tzanck cells are seen in which of the following conditions?
-Pemphigus vulgaris
-Erythema muliforme
-Systemic lupus erythmeatosus
-Behcet syndrome
Pemphigus vulgaris
The oral lesions in Teirter syndrome may resemble:
Geogrpahic tongue
Apthous ulcers are seen in each all of the following systemic disease EXCEPT:
-Behcet syndrome
-Langerhans cell disease
-Ulcerative colitis
Langerhans cell disease
The two cell types that histologically characterize Langerhans cell disease are:
Eoshinophils and lymphocytes
Which of the following is the form of Langerhans cell disease that is characterized by a triad of symptoms?
-Letterer-Siwe disease
-Hand-Schuller-Christian disease
-Eosinophils granuloma
-Behcet syndrome
Hand-Schuller-Christian disease
The most benign type of Langerhans cell disease is:
Eosinophils granuloma
The most characteristic oral manifestation of Sjogren syndrome is:
Which of the following statements is false?
-The bullae in pemphigus vulgaris are more fragile than those in bullous pemphigoid.
-Acantholysis of the epithelium is een in pemphigus vulgarus.
-The pemphigoid the separation of the epithelium from the connective tissue occurs at the basement membrane.
-Skin lesions are common in mucous membrane pemphigus
Skin lesions are common in mucous membrane pemphigoid
Which is the most distinct and definitive characteristic that distinguishes pemphigus from pemohigoid?
The histologic findings
Desquamative gingivits may be seen in :
-Cicaticaial pemphigoid
-Pemphigu vulgaris
-Lichen planus
-All of the above
All of the above
In angioedema involvementof which of the following tissues could create a life-threatening situation for the patient?
Which of the following pathologic conditions that produces a characteristic butterfly-shaped lesion on the face and oral ulcers, occurs more frequently in females than in males, and for which the result of a blood test is important to diagnosis?
-Erosive lichen planus
-Desquamative gingivitis
-Lupus erythmeatosus
Lupus erythmeatosus
Dissolution of the intercellular bridges of the prickle cell layer of the epithelium
Acquired immune response
A response of the body to injury that has memory of past exposure to a foreign substance and responds more quickly to a foreign substance when encountered a second time
A protein molecule, also called an immunoglobulin which is produced by plasma cells and reacts with a specific antigen
Any substance able to induce a specific immune response
Autoimmune disease
A disease characterized by tissue injury caused by a humoral cell or cell-medaited immune response against constituents of the body's own tissues.
B lymophocyte (B cell)
A lymphocyte, that mature without passing through the thymus; the B cell can later develop into a plasma cell that produces antibodies
Cell-mediated immunity
Immunity in which the predominant role is played by T lymphocytes
Cell product produced by the cells involved in the immune response
Humoral Immunity
Immunity in which B lymphocytes and antibodies plat the predominant role
A state of altered reactivity in which the body reacts to a foreign agent with an exaggerated immune response.
Immune complex
A combination of antibody and antigen
A deficiency of the immune response resulting from hypoactivityor decreased numbers of lymphoid cells
A protein, also called and antibody, synthesized by plasma cell in response to a specific antigen
LE cell
A cell that is a characteristic of lupus erythmeatosus and other autoimmune diseases; it is a mature neutrophil that has phagocytized a spherical inculsion derived from another neutrophil
Lymphoid tissue
Tissue composed of lymphocytes supported by a meshwork of connective tissue
A large tissue-bound mononuclear phagocyte derived from monocytes circulating in blood; macrophages become mobile when stimulated by inflammation and interact with lymphocytes in an immune response
Mucosal inflammation
Natural killer cell (NK cell)
A lymphocyte that is part of the body's initial innate immunity which by unknown mechanisms is able to directly destroy cells recognized as foreign
Nikolsky's sign
In some bullous diseases such as pemphigus bulgaris and bullous pemphigus the superficial epithelium separates easily from the basal layer on exertion of firm, sliding manual pressure
Rheumatoid factor
A protein, immunoglobulin M (IgM) found in serum and detectable on laboratory tests; it is associated with rheumatoid arthritis and other autoimmune diesases
T lymphocyte (T cell)
A lymphocyte that matures in the thymus before migrating to tissues; the T lymphocyte is responsible for cell-mediated immunity and may modulate the humoral immunity response
Abnormal dryness of the eyes