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pharmacology antiepileptic drugs
Terms in this set (20)
substances that prevent or reduce the severity of epileptic or other convulsive seizures
Prescription drugs that prevent or reduce the severity of epilepsy and different types of epileptic seizures, not just convulsive seizures.
a metabolic process in which a drug stimulates the production of enzymes that enhance its own metabolism, which leads to a reduction in drug concentrations
record of the electrical activity of the brain
A general term for any of a group of neurologic disorders characterized by recurrent episodes of convulsive seizures, sensory disturbances, abnormal behavior, loss of consciousness, or any combination of these.
Focal onset seizures
Seizures originating in a more localized region of the brain (formally called partial onset seizures).
Generalized onset seizures
seizures originating simultaneously in both cerebral hemispheres
overformation of gum tissue, often with phenytoin
Epilepsy in which there is no identifiable cause. Also known as idiopathic.
Excessive stimulation of neurons in the brain leading to a sudden burst of abnormal neuron activity that results in temporary changes in brain function, primarily affecting sensory and motor activity.
A seizure disorder characterized by generalized tonic-clonic convulsions that occur repeatedly; considered a true medical emergency
Seizures involving initial muscular contraction throughout the body (tonic phase), progressing to alternating contraction and relaxation (clonic phase).
Carbmazepine Side Effects
2. agranulocytosis (more rare than for Clozapine (Clozaril)
4. Derm reaactions
5. organ dysgenesis
[Ocycarbazepine has lesser side effects]
"Bone marrow suppression | use with(in): 14 days of MAO Inhibitors | Nefazodone | Non-nucleoside reverse transcriptase inhibitors"
Used in the treatment of uncomplicated absence seizures
Not effective for secondary generalized tonic-clonic seizures
Contraindication: known allergy
Adverse effects: GI and CNS effects
Drug interactions: hepatic enzyme-inducing drugs
Ethosuximide: side effects (memory trick)
Side Effects: fatigue, GI, headache, urticaria (itching), Stevens-Johnson syndrome
tching, and Stevens-
blocks voltage gated sodium channels
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