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Pharm Assignment 11 ?'s
Terms in this set (20)
Which of the following lipoproteins do the AHA/ACC lipid guidelines focus on treating with pharmacotherapy in patients without ASCVD?
Which of the following events would be considered to be due to ASCVD?
All of the above (ACS, Hx of MI, TIA, Angina)
What effects do statins have on cholesterol values?
4. Which of the following is a secondary cause of dyslipidemia?
Which type of therapy would be most appropriate to institute first for a 58-year-old female with type 2 diabetes and total cholesterol 210 mg/dL, HDL cholesterol 52 mg/dL, triglycerides 958 mg/dL, and LDL cholesterol 131 mg/dL?
Fenofibrate 160 mg daily
Which side effect can be caused by statin therapy?
New onset diabetes
A woman taking a drug for high LDL-cholesterol levels experiences muscle tenderness and pain with no apparent cause. Which agent is least likely to cause this adverse effect?
The following statins are metabolized through the CYP3A4 or 2C9 system EXCEPT:
Identify a baseline laboratory test that is required before initiating a statin.
Liver function tests
What is true regarding Omega-3 fatty acids (fish oils)?
all of the above; OTC products can differ dramatically in their EPA/DHA contentHigher doses of Omega-3 fatty acids (2-4 g/day) are used to lower triglyceridesThe product marketed as Vascepa contains only the EPA componentWhen using combination EPA/DHA preparations (Lovaza) in patients with very high triglycerides (>500 mg/dL) there may be an increase in LDL
Which of the following is the most accurate description of ezetimibe's mechanism of action?
Decreased gastrointestinal absorption of cholesterol
Which side effect can be caused by niacin therapy?
An otherwise healthy 58-year-old man is found to have an LDL-C level of 170 mg/dL, an HDL-C level of 50 mg/dL, and a triglyceride level of 105 mg/dL. He has no other risk factors for CHD. In addition to TLCs, which drug treatment is most appropriate for this patient?
Which of the following choices contains statins at doses that would achieve >50% reduction in LDL in most patients?
Atorvostatin 80mg, rosuvastatin 40 mg
Which one of the following statements is true about bile acid sequestrants (BAS)?
Other drugs should be taken one hour before or four hours after BAS
All of the following are risks for statin-induced myositis EXCEPT:
Use of a low-intensity statin therapy with a bile acid sequestrant (resin)
Mr. S has been placed on Simvastatin for his hypercholesterolemia/hyperlipidemia. How should he be instructed to take his medication?
Any time between supper and bedtime
A 38-year-old woman presents to your clinic today with new onset chest pain that occurs after walking a few blocks. Her father had a heart attack at age 40. Her diet is low in saturated fats and cholesterol. The patient is otherwise healthy and does not smoke. Her lipid panel today is: total cholesterol 350 mg/dL, HDL cholesterol 40 mg/dL, and triglycerides 120 mg/dL. According to the ACC/AHA guidelines, what intervention would be most appropriate for this patient?
Start rosuvastatin 20 mg daily
A 54-year-old man presents to your clinic today for routine follow-up on his type 2 diabetes mellitus. His mother and father are both living and have no known heart disease. He tries to follow a low sugar and low sodium diet. The patient smokes ½ pack of cigarettes per day but is otherwise healthy. His lipid panel today is: total cholesterol 250 mg/dL, HDL cholesterol 44 mg/dL, and triglycerides 180 mg/dL.
What is this patient's non-HDL cholesterol and LDL cholesterol?
206 mg/dl and 170 mg/dl
According to the ACC/AHA guidelines, what intervention would be most appropriate for the patient in the previous question?
Start atorvastatin 40mg daily
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