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21 terms

01_psych MOA update

STUDY
PLAY
amphetamine salts
blocks NE and DA reuptake into presynaptic neuron
methylphenidate
blocks NE and DA reuptake into presynaptic neuron
lisdexamfetamine
active metabolite blocks NE and DA reuptake
alprazolam
binds stereospecific BZ binding site on post-synaptic GABA receptor in CNS
clonazepam
binds BZ subunit on GABA receptor enhancing GABA activity
diazepam
A-type GABA receptor binding reduces neuronal depolarization
lorazepam
GABA receptor agonist
zolpidem
binds BZ receptor subunit of GABA-A receptor complex
prochlorperazine
blocks post synaptic mesolimbic D1 and D2 receptors
amitriptyline HCL
blocks membrane pump mechanism respnsible for absorption of serotonin and norepinephrine in serotonergic and adrenergic neurons; promoting neuronal activity
trazodone HCL
selective inhbition of serotonin reuptake potentiates serotonergic activity in the CNS
citalopram hydrobromide
serotonin reuptake inhibitor with minimal effects on neuronal NE and DA reuptake
fluoxetine HCL
serotonin reuptake inhibitor with minimal effects on neuronal NE and DA reuptake
paroxetine HCL
serotonin reuptake inhibitor with minimal effects on neuronal NE and DA reuptake
sertraline HCL
serotonin reuptake inhibitor with minimal effects on neuronal NE and DA reuptake
duloxetine
potentiates serotonergic and noradrenergic activity in the CNS
venlafaxine
potentiates serotonergic and noradrenergic activity in the CNS
aripiprazole
5-HT1A and D2 partial agonist; 5-HT2A antagonist
quetiapine
5-HT1A, 5-HT2, D1, H1, and adrenergic α 1/2 antagonist
olanzapine
DA and 5-HT2 antagonist
pregabalin
GABA analog; binds alpha-2-delta site of voltage-gated calcium channel in CNS