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diabetes doro
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Terms in this set (92)
common acute complication of T1D
DKA
common acute complication of T2D
hyperglycemic hyperosmotic state
which patients are more at risk of hyperglycemic hyperosmotic state
T2D + elderly patients
most common SE of insulin therapy
hypoglycemia
patient found unconscious who has diabetes: top 3 differentials
1. diabetic ketoacidosis
2. hyperosmolar non-ketotic state (or coma)
3. hypoglycemia
presenting symptoms of DKA
nausea, vomiting, abdominal pain
most common cause of DKA
not using insulin correctly
etiology of type 1 diabetes
1. autoimmune destruction of beta cells in the pancreas by T lymphocytes
2. don't make any insulin
islet cell antibodies (ICA)
glutamic acid decarboxylase antibodies (GAD)
insulin autoantibodies (IAA)
tyrosine phosphatase 2 protein antibodies (IA2)
ZnT8
etiology of type 2 diabetes
1. insulin resistance (often due to obesity, also a genetic factor)
2. after years of being insulin resistance, patients develop hyperglycemia and type 2 DM
poor eating habits/lots of carb exposure and lack of exercise exposes patients to large amounts of carbohydrates over time--> require a lot of insulin to take care of the carb load--> too much exposure to insulin over time leads to insulin resistance
why don't oral medications work for T1D patients?
there are no functioning beta cells
DKA vitals:
-BP
-HR
-RR
-blood glucose
BP: lower (due to dehydration)
HR: elevated (due to acidosis, dehydration)
RR: elevated (compensation for met acidosis)
blood glucose: elevated above 240-250 (due to lack of insulin)
breathing seen in DKA
Kussmaul breathing: deep fast breathing with fruity odor
1. metabolic acidosis--> respiratory compensation--> deep respirations
what causes the fruity breath odor in DKA?
acetone, one of the ketoacids
precipitating events of DKA
1. lack of insulin
2. stress
3. trauma
4. infection
DKA: acid/base disturbance seen
anion gap metabolic acidosis: due to ketones
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