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Benign & Malignant salivary gland tumors

Terms in this set (106)

What are the classifications of salivary gland tumors?
- Benign epithelial tumors
- Malignant epithelial tumors
- Mesenchymal tumors
- Lymphomas
- Metastatic tumors
What are 2 examples of benign epithelial tumors?
Pleomorphic adenoma
Monomorphic adenoma
What is the most common location of a pleomorphic adenoma?
parotid gland
what is the peak incidence of salivary gland tumors? what is the gender predilection?
- 6-7th decades
- females
Rank the following from most common to least common location of SGT:

- Submandibular gland
- Sublingual gland
- parotid gland
- minor glands (palate)
parotid > minor glands > submandibular > sublingual
What are some etiologic factors of SGT?
- radiation exposure
- genetic predisposition
- tobacco
- chemical carcinogens
- viruses
T/F: most Salivary Gland Tumors are malignant
FALSE! most are benign
Rank the following from most common to least common location of a MALIGNANT SGT:

- Submandibular gland
- Sublingual gland
- parotid gland
- minor glands (palate)
sublingual > minor > submandibular > parotid
____ is a benign tumor composed of cells exhibiting the ability to differentiate to epithelial (ductal and nonductal cells) & mesenchymal (chondroid, myxoid, and osseous) cells
pleomorphic adenoma (mixed tumor)
What type of tumor is this?
pleomorphic adenoma
What is the most common salivary neoplasm?
pleomorphic adenoma
What type of cells does a pleomorphic adenoma come from?
arise from a mixture of ductal & myoepithelial cells
What do you see on the histo for a pleomorphic adenoma?
- remarkable microscopic diversity
- although the basic pattern is highly variable, individual cells are rarely "pleomorphic"
- "mixed tumor" refers to the mesenchyme- appearing component
What are the clinical features of a pleomorphic adenoma?
painless, slowly growing, freely moveable, firm mass
- most common site is the parotid gland
- palate is most common in minor salivary glands
what are the predilections for a pleomorphic adenoma?
- most common is YA 30-50 yo
- Females > males
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