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wise nephro CAM

Terms in this set (23)

Artichoke
increases risk of nephrotoxicity
Bitter Melon
can be used for psoriasis, colitis/ C , kidney stones but lacks evidence
Black Cohosh
pre caution
- Use in caution or avoid inpatients with a history of breast cancer or women at risk for breast cancer or other hormone-sensitive cancers/conditions; liver disease; patients with protein S deficiency (increased risk of thrombosis); and patients who have had a kidney transplant

- May elevate LFTs. May cause kidney transplant rejection. Inhibits ALL CYP450 isoenzymes but is most potent against 2D6,2B6, and 2C19 in that order.
Caffeine (Coffee, black tea, guarana, cocoa, yerba mate, guarane, kombucha)
known side effects
HA, diuresis, dyspepsia increases blood pressure, tachycardia, nervousness, insomnia, agitation, arrhythmia, tinnitus, dizziness
Cannabis
Metabolites are excreted renally-metabolites may appear in urine for 10 days or more after a single exposure and for several weeks after chronic exposure. THC causes bronchodilation and broncho spasm and with long-term use can cause impaired lung function and COPD.
Chamomile
CYP 2D6 inhibitor. Increases creatinine output for up to two weeks later use.
Clove
mechanism

CNS stimulation, increases heart-rate and contractility, increases blood pressure, stimulates gastric acid secretion, causes diuresis, relaxes bronchial smooth muscle and may increase triglyceride production
CoQ10/CoEnzyme Q 10
mechanism

as a fat-soluble vitamin-like substance found in heart, liver, kidney and pancreas predominantly and acts as an antioxidant to remove peroxides. It also acts at the mitochondria to reduce loss of dopamine in platelets.
Cranberry
Evidence-based Uses for UTI, PUD

Avoid or use with caution inpatients with an ASA allergy, orhistory of kidney stones

mechanism

contains salicylic acid so acts as anti-inflammatory, anticoagulant, and analgesic. It also inactivates many pathogens in the urinary tract by preventing them from adhering to the bladder wall

other uses but lack evidence
diabetes, BPH, cold, influenza, CAD, memory, kidney stones
Ephedra
side effects
chest pain, QT prolongation, anxiety, tremor, increased BP, kidney stones
Ginkgo
evidence base use
Alcoholic withdrawal sx, MS,PMS, Vaginal dryness, PVD, Depression, UTI, dementia
Glucosamine
evidence base use

cataracts, OA/joint pain, UTIs

other uses with lack of evidence
urinary incontinence, GERD, RA,TMJ+I39
L-Arginine
other uses with lack of evidence
kidney disease, MI, CHF, dementia, cavities
Licorice(glycyrrhizin containing) -Licorice flavoring has been de-glycyrrhizinatedso it is safe =DGL)
side effects
N/V, angina, hypertension, water retention, electrolyte imbalances (potassium)

precautions
Avoid or use with caution inpatients with heart disease, hormone sensitive cancers/conditions, HTN, hypertonia, hypokalemia, kidney insufficiency, sexual dysfunction
Periwinkle /Vinpocetine
other uses with lack of evidence
macular degen, hearing loss, stroke, tinnitus, urinary incontinence, neuroprotection, weight loss
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