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Pathophysiology 18 Questions

Workbook questions and quiz questions
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Schizophrenia
Thought disorders are associated with?
Schizophrenia
Hypoactive DLPFC (dorsolateral prefontal cortex) with decreased blood flow lowers GABA, which is the inhibitory neurotransmitter for this disorder.
Depression
Unremitting feelings of sadness and despair
Mania
Feelings of gradiosity
Mania
Task Distranction
Obsessive-compulsive disorder
Triggering Cues
Generalized anxiety disorder
Excessive worry
Schizophrenia
Exhibit happiness when recalling a terrible event
Depression
Unable to express pleasure
Mania
Elevated levels of brain serotonin
Depression
Deficit in brain norepinephrine
Panic Disorder
Intense autonomic arousal
Schizophrenia
Neurodevelopmental defects
Schizophrenia
Elevated dopaminergic transmission
Depression
Deficit in brain serotonin
Schizophrenia
Ventricular enlargement
Obsessive-compulsive disorder
Decreased serotonin synthesis in prefrontal cortex
Depression
Elevated levels of cortisol
Panic Disorder
Difficult breathing
Post-traumatic stress disorder
Stimuli avoidance
Panic Disorder
Racing heart
Generalized anxiety disorder
Panic Disorder
GABA-benzodiasepine receptor disorder
Post-traumatic stress disorder
Flashbacks
Panic Disorder
Biofeedback therapy
Schizophrenia
Psychotic episode
C. Disruption of thoughts
Which of the following BEST describes schizophrenia?

A. Positive personality
B. Negative personality
C. Disruption of thoughts
D. Constant hallucinations
D. Concordance between siblings is 15%.
Which of the following is a TRUE statement regarding the epidemiology of schizophrenia?

A. If a mother has twins, both twins will have schizophrenia 100% of the time.
B. Ten percent of the general population will have schizophrenia.
C. It is a simple genetic transmission.
D. Concordance between siblings is 15%.
A. Schizophrenia may result from neurodevelopmental defects.
A schizophrenic woman becomes pregnant. Which of the following is a TRUE statement regarding her offspring?

A. Schizophrenia may result from neurodevelopmental defects.
B. Research does not indicate any environmental involvement in schizophrenia.
C. An early brain effect manifests immediately.
D. There are no suspected alterations in brain structure.
C. Decreased glutamic acid decarboxylase
A. Schizophrenia may result from neurodevelopmental defects.
A. Levodopa
Drugs that increase dopamine transmission such as levodopa, cocaine, and amphetamine may produce psychosis at high doses. Traditional antipsychotic drugs have a high affinity for dopamine receptors, including chlorpromazine, fluphenazine, and haloperidol, and reduce psychotic states.
Which of the following drugs may actually cause psychosis at high doses?

A. Levodopa
B. Chlorpromazine
C. Fluphenazine
D. Haloperidol
B. Increased secretion of dopamine may contribute to positive symptoms.
Increased secretion of dopamine may contribute to positive symptoms. Negative symptoms may result from decreased dopaminergic transmission. Learning and memory are related to glutamic acid. Decreased concentrations of glutamic acid have been found in the CSF of schizophrenic individuals.
Which of the following is a TRUE statement regarding dopamine in relation to schizophrenia?

A. Negative symptoms result from increased dopaminergic transmission.
B. Increased secretion of dopamine may contribute to positive symptoms.
C. It is involved in learning and memory.
D. It is found in increased concentrations in CSF.
D. Neutral symptoms
Which of the following is NOT one of the three dimensions of schizophrenia?

A. Psychotic symptoms
B. Negative symptoms
C. Disorganized symptoms
D. Neutral symptoms
D. Hallucination
A man states he is hearing voices instructing him to steal money from the church. This perception is which of the following?

A. Delusion
B. Disorganized speech
C. Disorganized behavior
D. Hallucination
C. Anhedonia
An individual suffering from schizophrenia is unable to experience emotions, especially pleasure. Which of the following terms describes this?

A. Alogia
B. Avolition
C. Anhedonia
D. Aphasia
A. It is a sustained emotional state.
Which of the following is a TRUE statement regarding a mood disorder?

A. It is a sustained emotional state.
B. It is a disruption of thought.
C. Lifetime prevalence rate for depression is 1%.
D. Two percent of those with major depression develop bipolar disorder.
B. Depression occurs with deficits in brain norepinephrine.
Depression has been noted with deficits in norepinephrine, dopamine, and serotonin
Which of the following is TRUE regarding mood disorders?

A. The hypothalamic-pituitary-adrenal (HPA) system hormones are decreased in a large percentage of individuals with major depression.
B. Depression occurs with deficits in brain norepinephrine.
C. Environmental factors have no role in depression.
D. There is no genetic role in depression.