Fred's blood was determined to be AB positive. What does this mean?
There are no antibodies to A, to B, or to Rh antigens in the plasma.
Sickling of red blood cells can be produced in those with sickle-cell anemia by ________.
travel at high altitude and vigorous exercise
All of the following conditions impair coagulation except ________.
When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother?
when the father is Rh-
Complications of aplastic anemia generally do not include ________.
increase of leukocytes as a result of erythrocyte loss
Blood is a ________.
What organ in the body regulates erythrocyte production?
The formed element ________ can kill parasitic worms.
A(n) ________ is a committed granular leukocyte stem cell that produces neutrophils.
The rarest leukocyte is the ________.
Potent platelet aggregates that attract more platelets to the site of an injury are ________ and ________.
ADP and Thromboxane Serotonin
The universal recipient blood type is ________.
When monocytes migrate into the interstitial spaces, they are called ________.
Destruction of the hematopoietic components of red marrow leads to a condition called ________.
________ is the stage of development in the life of an erythrocyte during which the nucleus is ejected.
Hemoglobin is composed of ________ polypeptide chains.
List the general factors that limit normal clot growth
removal of clotting factors
Aspirin - an antiprostaglandin that inhibits thromboxane A2 Heparin - an anticoagulant used clinically for pre- and postoperative cardiac care Warfarin (trade name Coumadin) - used for those prone to atrial fibrillation
When are whole blood transfusions routinely given?
Substantial and rapid blood loss
List the most common causes of bleeding disorders
Thrombocytopenia - condition of decreased circulating platelets with vitamin K deficiency and defective clotting cascade
List one example for each of these three functions of blood: distribution, regulation, and protection
Distribution - delivering O2 from lungs and waste Regulation - maintenance of normal ph in body tissues Protection - prevention of blood loss
List the granulocytes and describe their granules
Neutrophil - fine, faint pink granules Eosinophil - full of pink-orange granules Basophil - large dark deep purple ganules
Why is iron not stored or transported in its free form? In what form(s) is it stored or transported in blood?
Because iron can be toxic. Intracellular iron is stored in protein-iron complexes such as ferritin and hemosiderin.
*FYI* The body stores iron in Hb (65%), the liver, spleen, and bone marrow Circulating iron is loosely bound to the transport protein transferrin
What determines whether blood is bright red or a dull, dark red?
the amount of oxygen
What is the buffy coat found in centrifuged whole blood?
Leukocytes and platelets
Name the granulocytes and state their average percentage in whole blood.