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SET #4 101-125

STUDY
PLAY
epistasis
the suppression of a gene by the effect of an unrelated gene
penetrant
percentage of individuals with a genotype who have an associated phenotype
expressivity
the degree to which a genotype is expressed in an individual
pleiotropic
a single gene determines more than one phenotype for and organism.
phenocopy
An environmentally caused trait that occurs in a familial pattern, mimicking inheritance
genetic heterogeneity
A phenotype that can be caused by variants of any of several genes
heteroplasmic
mitochondria within same cell having different alleles of gene
linked
in genetics, describes two or more genes that tend to be inherited together
recombinant genotype
a series of alleles on a chromosome that differs from the series of either parent
linkage map
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes.
haplotype
a combination of genes or DNA sequences that are inherited as a single unit
heterogametic sex
2 unlike chromosomes
homogametic sex
2 like chromosomes
psuedoautosomal regions
Small regions of the X & Y chromosomes where they are homologous which allows the two to pair.
hemizygous
the single set of genes that males acquire from their mother's X chromosome
x inactivation
in female mammals, the inactivation of one X chromosome in each somatic cell
manifesting heterozygote
a carrier for a homozygous condition demonstrates clinical manifestations.....can be due to skewed X inactivation in women.....(DMD and hemophilia)
sex limited traits
a characteristic controlled by autosomal genes that is phenotypically exhibited in only one of the two sexes.
sex influenced gene
Trait that is caused by a gene whose expression differs in females.
genomic imprinting
a phenomenon in which expression of an allele in offspring depends on whether the allele is inherited from the male or female parent
multifactorial trait
variation in traits caused by genetic and environmental or lifestyle factors
polygenic trait
trait controlled by two or more genes
empiric risk
the average chance that a disease will occur in a family based upon experience and observation of a study population not a theory.
heritability
the proportion of variation among individuals that we can attribute to genes
concordance
trait similarity