Upgrade to remove ads
Only $35.99/year

L17- PUD Pharmacology

Terms in this set (104)

_ results when corrosive action of gastric acid and pepsin overcome mucosal defense mechansims
peptic ulceration
_ can occur if excess production of acid or a breakdown of mucosal defense mechanisms
peptic ulceration
bacterial species that may be critical factor in development of peptic ulcers
h.pylori
cells of stomach that produce acid
parietal cells
_ in stomach parietal cells transport HCl into the lumen of the stomach
proton pumps
hormone released by pyloric and duodenal areas of GI tract in response to food ingestion; stimulates acid production from stomach parietal cells
gastrin
molecule that has a permissive effect on PNS and gastrin in the production of stomach acid from parietal cells
histamine
_ nervous system stimulates production of stomach acid from parietal cells
parasympathetic
_ receptor on parietal cell binds histamine to stimulate acid production
H2
the 3 control mechanisms of acid secretion by parietal cells
PNS, gastrin, histamine
without the action of _, neither of the other 2 control mechanisms of acid secretion by parietal cells would be as effective
histamine
primary defense mechanism in stomach against the harsh acidic environment that exists within
mucosal barrier
mucus of stomach is produced and secreted by _ cells- is made up of glycoproteins, water, electrolytes
goblet
most important electrolyte that makes up mucus
bicarbonate
_ adheres to epithelial cells that line stomach to protect them from erosive action of acid and pepsin
mucus
Sets found in the same folder