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mouse terminology 🐁

Terms in this set (22)

are nu/nu & SKID (scid/scid) inbred strains or inbred mutant strains?
inbred mutant strains
conventional
animals bred w/ no special precautions & possess unknown & various microorganisms
outbred strains (stocks)
random breeding to achieve genetic variations, Heterozygous
DBA
brown
Balb/c
albino
what strains are used in oncology studies?
inbred mutant strains
transgenic
altering genetic makeup, DNA is introduced into the developing eggs. genes can be taken away
what is a knockout mouse?
transgenic
SKID (scid/scid)
severe combined immunodifferent
specific pathogen free (SPF)
free from specific pathogenic organisms
inbred strains
brother / sister mating
C57BL
black
germ free or axenic
animals derived from hysterectomy. free from any microorganisms, lacks normal flora
congenic
a mouse/mice bred genetically different at one particular locus
are C57BL, Balb/c, C3H, & DBA inbred strains or inbred mutant strains?
inbred strains
barrier-sustained
maintained under sterile conditions in a barrier unit
isogenic
20 consecutive generalization of brother/sister matings, genetically Homozygous
nu/nu
nude, has no hair & immune deficient
C3H
agouti
recombinant
molecular cloning to make a new DNA sequence, combing genetic material
gnotobiotic
germ free mice that have been introduced to 1 or 2 known non-pathogenic microorganisms, defined flora
F1 hybrid
results of mating an isogenic mouse from one strain w/ an isogenic mouse from another strain (homozygous & hybrid vigor)
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